Rectal adenocarcinoma in the eye: An unexpected destination.

Autor: Lahham EE; Department of Radiation Oncology, Augusta Victoria Hospital, East Jerusalem, Palestinian Territory., Alsahouri MI; Faculty of Medicine, Palestine Polytechnic University, Hebron, Palestine., Alsalah QA; Faculty of Medicine, Palestine Polytechnic University, Hebron, Palestine., Billan S; Head and Neck Unit, Joseph Fishman Oncology Center, Rambam Health Care Campus, Haifa, Israel., Atrash F; Department of Radiation Oncology, Augusta Victoria Hospital, East Jerusalem, Palestinian Territory.
Jazyk: angličtina
Zdroj: SAGE open medical case reports [SAGE Open Med Case Rep] 2024 Mar 28; Vol. 12, pp. 2050313X241242608. Date of Electronic Publication: 2024 Mar 28 (Print Publication: 2024).
DOI: 10.1177/2050313X241242608
Abstrakt: Colorectal cancer ranks third in cancer incidence in the United States, commonly metastasizing to the liver and lungs. Despite its high prevalence, colorectal cancer with intraocular metastasis is exceedingly rare, with only a few cases reported in the literature. This study presents a 58-year-old male, previously treated for rectal adenocarcinoma with liver and lung metastases, who developed choroidal metastasis causing visual impairment. Despite radiotherapy, moderate improvement was observed, and subsequent disease progression led to systemic chemotherapy. Intraocular metastasis, primarily affecting the choroid, is infrequent, often originating from breast and lung cancers. The presented case, originating from primary KRAS wild-type rectal cancer, adds to the limited gastrointestinal-tract-related occurrences. This report underscores the importance of recognizing intraocular metastasis in colorectal cancer, contributing valuable insights for improved understanding and potential guidance for future clinical decisions. Choroidal metastasis carries a poor prognosis, emphasizing the need for tailored management strategies.
Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
(© The Author(s) 2024.)
Databáze: MEDLINE