Topical everolimus therapy for epidermal nevi associated with woolly hair nevus in a patient with a mosaic HRAS mutation.

Autor: Singh A; Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Gorell ES; Division of Dermatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Lucky AW; Division of Dermatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Jazyk: angličtina
Zdroj: Pediatric dermatology [Pediatr Dermatol] 2024 Sep-Oct; Vol. 41 (5), pp. 871-873. Date of Electronic Publication: 2024 Apr 01.
DOI: 10.1111/pde.15605
Abstrakt: A patient with woolly hair nevus syndrome, presented with epidermal facial nevi by the age of 12 years. Despite transient improvement with topical 1% sirolimus cream, the facial nevus grew larger. The patient was then treated with topical 1% everolimus cream resulting in a reduction in the size of the nevus. This case highlights a novel use of topical 1% everolimus cream, which previously has not been used to treat epidermal nevi.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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