The role of CT brain findings in the early diagnosis of infantile encephalitic beriberi.

Autor: Wani NA; Department of Pediatric Radiology, Govt Medical College, Srinagar, J&K, India. nisar.wani@yahoo.com., Malik I; Department of Pediatrics, Govt Medical College, Srinagar, J&K, India., Tariq S; Department of Pediatrics, Govt Medical College, Srinagar, J&K, India., Bhat AS; Department of Pediatrics, Govt Medical College, Srinagar, J&K, India., Qureshi UA; Department of Pediatrics, Govt Medical College, Srinagar, J&K, India.
Jazyk: angličtina
Zdroj: Neuroradiology [Neuroradiology] 2024 Jun; Vol. 66 (6), pp. 1043-1047. Date of Electronic Publication: 2024 Apr 01.
DOI: 10.1007/s00234-024-03346-7
Abstrakt: Background: Thiamine deficiency disease may occur in infants from thiamine-deficient mothers in developing countries, as well as in infants fed solely with soy-based formula. Thiamine deficiency in infants may present with acute neurological manifestations of infantile encephalitic beriberi.
Objective: To review the role of noncontrast CT brain findings in infantile encephalitic beriberi in early diagnosis.
Materials and Methods: A retrospective review of noncontrast CT scans of the brain in 21 infants with acute-onset infantile encephalitic beriberi was carried out.
Results: On noncontrast-enhanced CT brain, hypodense lesions were seen symmetrically in the putamen in all the babies; symmetric hypodensities were seen in the caudate nuclei in 14/21 (67%), in dorsomedial thalami/hypothalamic/subthalamic area in 4/21 (19%), and in the globi pallidi in 2/21 (9.5%) of the infants.
Conclusion: Recognition of symmetrical hypodense lesions in the basal ganglia and medial thalami/hypothalamic/subthalamic area on noncontrast CT scan of the brain are important early features to recognize in encephalitic beriberi in at-risk infants.
Advances in Knowledge: IEBB is a cause of hypodense bilateral basal ganglia and may be identified by this finding in the appropriate clinical settings.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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