Environmental epigenetics: Exploring phenotypic plasticity and transgenerational adaptation in fish.

Autor: Abdelnour SA; Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, 44519, Egypt. Electronic address: Samehtimor86@gmail.com., Naiel MAE; Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, 44519, Egypt., Said MB; Laboratory of Microbiology, National School of Veterinary Medicine of Sidi Thabet, University of Manouba, Manouba, 2010, Tunisia; Department of Basic Sciences, Higher Institute of Biotechnology of Sidi Thabet, University of Manouba, Manouba, 2010, Tunisia., Alnajeebi AM; Department of Biochemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia., Nasr FA; Biology Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia., Al-Doaiss AA; Biology Department, College of Science, King Khalid University, P.O. Box 9004, Abha, 61413, Saudi Arabia., Mahasneh ZMH; Department of Animal Production, School of Agriculture, The University of Jordan, Amman, 11942, Jordan., Noreldin AE; Department of Histology and Cytology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, Egypt.
Jazyk: angličtina
Zdroj: Environmental research [Environ Res] 2024 Jul 01; Vol. 252 (Pt 1), pp. 118799. Date of Electronic Publication: 2024 Mar 27.
DOI: 10.1016/j.envres.2024.118799
Abstrakt: Epigenetics plays a vital role in the interaction between living organisms and their environment by regulating biological functions and phenotypic plasticity. Considering that most aquaculture activities take place in open or natural habitats that are vulnerable to environmental changes. Promising findings from recent research conducted on various aquaculture species have provided preliminary evidence suggesting a link between epigenetic mechanisms and economically valuable characteristics. Environmental stressors, including climate changes (thermal stress, hypoxia, and water salinity), anthropogenic impacts such as (pesticides, crude oil pollution, nutritional impacts, and heavy metal) and abiotic factors (infectious diseases), can directly trigger epigenetic modifications in fish. While experiments have confirmed that many epigenetic alterations caused by environmental factors have plastic responses, some can be permanently integrated into the genome through genetic integration and promoting rapid transgenerational adaptation in fish. These environmental factors might cause irregular DNA methylation patterns in genes related to many biological events leading to organs dysfunction by inducing alterations in genes related to oxidative stress or apoptosis. Moreover, these environmental issues alter DNA/histone methylation leading to decreased reproductive competence. This review emphasizes the importance of understanding the effects of environmentally relevant issues on the epigenetic regulation of phenotypic variations in fish. The goal is to expand our knowledge of how epigenetics can either facilitate or hinder species' adaptation to these adverse conditions. Furthermore, this review outlines the areas that warrant further investigation in understanding epigenetic reactions to various environmental issues.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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