Remote Control of Energy Transformation-Based Cancer Imaging and Therapy.

Autor: Xu H; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea., Kim D; Department of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea., Zhao YY; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea., Kim C; Department of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea., Song G; State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China., Hu Q; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Jinan, 250014, China., Kang H; Department of Materials Science and Engineering, Korea University, Seoul, 02841, Republic of Korea.; College of Medicine, Korea University, Seoul, 02841, Republic of Korea., Yoon J; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
Jazyk: angličtina
Zdroj: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Jul; Vol. 36 (27), pp. e2402806. Date of Electronic Publication: 2024 Apr 05.
DOI: 10.1002/adma.202402806
Abstrakt: Cancer treatment requires precise tumor-specific targeting at specific sites that allows for high-resolution diagnostic imaging and long-term patient-tailorable cancer therapy; while, minimizing side effects largely arising from non-targetability. This can be realized by harnessing exogenous remote stimuli, such as tissue-penetrative ultrasound, magnetic field, light, and radiation, that enable local activation for cancer imaging and therapy in deep tumors. A myriad of nanomedicines can be efficiently activated when the energy of such remote stimuli can be transformed into another type of energy. This review discusses the remote control of energy transformation for targetable, efficient, and long-term cancer imaging and therapy. Such ultrasonic, magnetic, photonic, radiative, and radioactive energy can be transformed into mechanical, thermal, chemical, and radiative energy to enable a variety of cancer imaging and treatment modalities. The current review article describes multimodal energy transformation where a serial cascade or multiple types of energy transformation occur. This review includes not only mechanical, chemical, hyperthermia, and radiation therapy but also emerging thermoelectric, pyroelectric, and piezoelectric therapies for cancer treatment. It also illustrates ultrasound, magnetic resonance, fluorescence, computed tomography, photoluminescence, and photoacoustic imaging-guided cancer therapies. It highlights afterglow imaging that can eliminate autofluorescence for sustained signal emission after the excitation.
(© 2024 The Authors. Advanced Materials published by Wiley‐VCH GmbH.)
Databáze: MEDLINE
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