Examining identical twins undergoing bariatric surgery: the single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) approach.

Autor: Menon R; General Surgery Department, Ipswich Hospital, Chelmsford Ave, Ipswich, QLD 4305, Australia., Lockie P; General Surgery Department, Ipswich Hospital, Chelmsford Ave, Ipswich, QLD 4305, Australia.
Jazyk: angličtina
Zdroj: Journal of surgical case reports [J Surg Case Rep] 2024 Mar 27; Vol. 2024 (3), pp. rjae192. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).
DOI: 10.1093/jscr/rjae192
Abstrakt: Studies in monozygotic (MZ) twins may help researchers elucidate the complex relationships between genetic and environmental factors on weight loss. We present a world first of MZ twins who have undergone the single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) procedure who have identical weights 3 years post-operatively. Two MZ twin 49-year-old females were assessed preoperatively and were indicated for the SADI-S procedure. They underwent surgery in 2020 by the same surgical team. Three years later post-operatively they had identical weights of 62 kg (and a BMI of 23) and %EWL of 126 and 124% respectively. SADI-S is a novel bariatric procedure for morbid obesity. Studies have found concordant epigenetic patterns in patients who have undergone bariatric surgery as well as MZ twins who have hypocaloric diets. Genetics exert a strong influence in weight management. Surgical management as well as a collaborative multidisciplinary approach is beneficial in supporting long lasting weight loss in bariatric surgery.
Competing Interests: None declared.
(Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.)
Databáze: MEDLINE
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