Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants.

Autor: Stellmaker R; Australian Lymphoedema Education Research and Treatment Program (ALERT), Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde, New South Wales, Australia., Thompson B; Australian Lymphoedema Education Research and Treatment Program (ALERT), Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde, New South Wales, Australia., Mackie H; Australian Lymphoedema Education Research and Treatment Program (ALERT), Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde, New South Wales, Australia., Koelmeyer L; Australian Lymphoedema Education Research and Treatment Program (ALERT), Faculty of Medicine, Health and Human Sciences, Macquarie University, North Ryde, New South Wales, Australia.
Jazyk: angličtina
Zdroj: Clinical obesity [Clin Obes] 2024 Aug; Vol. 14 (4), pp. e12658. Date of Electronic Publication: 2024 Mar 28.
DOI: 10.1111/cob.12658
Abstrakt: Lipoedema is the disproportionate accumulation of adipose tissue in the lower body, often associated with hormonal changes in women. Lipoedema is commonly misdiagnosed as lymphoedema or obesity due to similarities in appearance. The aim of this study is to compare body composition and fluid measures of women with lipoedema, lymphoedema, and matched control participants, to determine differences that may help distinguish between each condition. One hundred and eleven participants aged over 18, who presented with the complaint of leg swelling and underwent indocyanine green lymphography were included in this study. Our analysis showed that the individuals with lymphoedema had a significantly higher overall total body water (lymphoedema: 9.6 ± 4.2 L, lipoedema: 7.4 ± 2.3 L, control: 7.5 ± 1.8 L; p < .001) and extracellular fluid (lymphoedema: 4.6 ± 1.6, lipoedema: 3.4 ± 1.0 L, control: 3.5 ± 0.7 L; p < .001) in the legs when compared to individuals with lipoedema and matched control participants. Individuals with lipoedema had a significantly higher overall fat mass as a percentage of body weight when compared to individuals with lymphoedema (lymphoedema: 33.1% ± 9.5%, lipoedema: 39.4% ± 6.5%; p = .003). We are unable to distinguish between individuals with lipoedema and control participants, therefore further research needs to be conducted to help reduce misdiagnosis.
(© 2024 The Authors. Clinical Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation.)
Databáze: MEDLINE
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