An Overview of Research for the Application of a Novel Biofilm-Preventing Surgical Irrigation System for Total Joint Arthroplasty Procedures in Order to Reduce the Risk of Periprosthetic Infection.

Autor: Sequeira SB; Medstar Union Memorial Hospital, Baltimore, Maryland., Myntti MF; 2Next Science, Jacksonville, Florida., Lee J; 2Next Science, Jacksonville, Florida., Mont MA; The Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, Maryland.
Jazyk: angličtina
Zdroj: Surgical technology international [Surg Technol Int] 2024 Jul 15; Vol. 44, pp. 320-325.
DOI: 10.52198/24.STI.44.OS1780
Abstrakt: Periprosthetic joint infection (PJI) is a serious postoperative complication in joint arthroplasty procedures that carries substantial morbidity and mortality associated with it. Several strategies have been developed both in the preoperative, perioperative, and postoperative periods to both combat and prevent the development of this devastating complication. Intraoperative irrigation is an important modality used during arthroplasty procedures prior to the implantation of final components that seeks to eradicate any biofilm formation. In this updated review, we discuss the XPERIENCE™ Advanced Surgical Irrigation solution (Next Science, Jacksonville, Florida) and the various completed, ongoing, and planned basic science and clinical investigations associated with it. Although there is already an impressive body of literature supporting its widespread utilization, future basic and clinical trials will continue to be performed to comprehensively characterize the effect this antimicrobial solution has on eliminating the risk of PJI following arthroplasty procedures.
Databáze: MEDLINE