Quantitative measurement of hair diameter diversity as a diagnostic indicator of androgenetic alopecia in Korean males: A cross-sectional study.

Autor: Park HU; Department of Dermatology, Hanyang University Medical Center, Myongji Hospital, Goyang, Republic of Korea.; Department of Dermatology, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea., Chung KB; Department of Dermatology, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim DY; Department of Dermatology, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jazyk: angličtina
Zdroj: JAAD international [JAAD Int] 2024 Feb 15; Vol. 15, pp. 121-126. Date of Electronic Publication: 2024 Feb 15 (Print Publication: 2024).
DOI: 10.1016/j.jdin.2024.02.005
Abstrakt: Background: The conventional 20% threshold for hair diameter diversity (HDD), widely accepted for diagnosing androgenetic alopecia (AGA) in the vertex area, has not quantitatively analyzed.
Objective: To validate the HDD 20% threshold for AGA and develop a refined, Korean-specific criterion.
Methods: This study involved 240 male patients with AGA, categorized by the V stages of the basic and specific classification. Phototrichogram images of the vertex region were analyzed using Image J software for hair thickness measurement.
Results: Receiver operating characteristic curve analysis determined the 45 μm hair diameter threshold as the most diagnostic for AGA, with an area under the curve value of 0.884 and a Youden index of 0.659. Optimal AGA diagnosis was achieved when over 21% of hair had a diameter of ≤45 μm.
Limitations: Restriction to Korean male limits its applicability to a broader population, and using a specific hair diameter threshold does not account for individual variations in hair characteristics.
Conclusion: The study validates the conventional HDD 20% threshold and proposes a more appropriate 45 μm threshold for Korean males, beyond the 40 μm. It concludes that while the HDD 20% remains a key method for early detection of vertex AGA, the definition of thin hair should be ethnicity-specific.
Competing Interests: None disclosed.
(© 2024 by the American Academy of Dermatology, Inc. Published by Elsevier Inc.)
Databáze: MEDLINE