Advanced Data Processing of Pancreatic Cancer Data Integrating Ontologies and Machine Learning Techniques to Create Holistic Health Records.

Autor: Manias G; Department of Digital Systems, University of Piraeus, 18534 Piraeus, Greece., Azqueta-Alzúaz A; Facultad de Informática, Universidad Politécnica de Madrid, 28040 Madrid, Spain., Dalianis A; Athens Technology Center S.A., 15233 Athens, Greece., Griffiths J; Information Catalyst, S.L., 46800 Xàtiva, Spain., Kalogerini M; Athens Technology Center S.A., 15233 Athens, Greece., Kostopoulou K; Innovation Sprint, 1200 Brussels, Belgium., Kouremenou E; Department of Digital Systems, University of Piraeus, 18534 Piraeus, Greece., Kranas P; LeanXscale, 28223 Madrid, Spain., Kyriazakos S; Innovation Sprint, 1200 Brussels, Belgium., Lekka D; Innovation Sprint, 1200 Brussels, Belgium., Melillo F; Engineering Ingegneria Informatica SpA, 00144 Rome, Italy., Patiño-Martinez M; Facultad de Informática, Universidad Politécnica de Madrid, 28040 Madrid, Spain., Garcia-Perales O; Information Catalyst, S.L., 46800 Xàtiva, Spain., Pnevmatikakis A; Innovation Sprint, 1200 Brussels, Belgium., Torrens SG; Hospital de Denia Marina Salud S.A., 03700 Alicante, Spain., Wajid U; Information Catalyst, S.L., 46800 Xàtiva, Spain., Kyriazis D; Department of Digital Systems, University of Piraeus, 18534 Piraeus, Greece.
Jazyk: angličtina
Zdroj: Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Mar 07; Vol. 24 (6). Date of Electronic Publication: 2024 Mar 07.
DOI: 10.3390/s24061739
Abstrakt: The modern healthcare landscape is overwhelmed by data derived from heterogeneous IoT data sources and Electronic Health Record (EHR) systems. Based on the advancements in data science and Machine Learning (ML), an improved ability to integrate and process the so-called primary and secondary data fosters the provision of real-time and personalized decisions. In that direction, an innovative mechanism for processing and integrating health-related data is introduced in this article. It describes the details of the mechanism and its internal subcomponents and workflows, together with the results from its utilization, validation, and evaluation in a real-world scenario. It also highlights the potential derived from the integration of primary and secondary data into Holistic Health Records (HHRs) and from the utilization of advanced ML-based and Semantic Web techniques to improve the quality, reliability, and interoperability of the examined data. The viability of this approach is evaluated through heterogeneous healthcare datasets pertaining to personalized risk identification and monitoring related to pancreatic cancer. The key outcomes and innovations of this mechanism are the introduction of the HHRs, which facilitate the capturing of all health determinants in a harmonized way, and a holistic data ingestion mechanism for advanced data processing and analysis.
Databáze: MEDLINE
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