| Autor: |
Tsiakalos A; Leto General, Maternity-Gynecological Clinic, 11524 Athens, Greece., Schinas G; School of Medicine, University of Patras, 26504 Rio, Greece., Karatzaferis A; Alpha Bank SA, 10564 Athens, Greece., Rigopoulos EA; School of Medicine, University of Patras, 26504 Rio, Greece., Pappas C; Euroclinic Athens, 11521 Athens, Greece., Polyzou E; School of Medicine, University of Patras, 26504 Rio, Greece., Dimopoulou E; Hellenic Institute for the Study of Sepsis, 11528 Athens, Greece., Dimopoulos G; 3rd Department of Critical Care, Evgenidio Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece., Akinosoglou K; School of Medicine, University of Patras, 26504 Rio, Greece.; Department of Internal Medicine and Infectious Diseases, University General Hospital of Patras, 26504 Rio, Greece. |
| Abstrakt: |
Primary Epstein-Barr virus (EBV) infection manifests with diverse clinical symptoms, occasionally resulting in severe complications. This scoping review investigates the rare occurrence of acute acalculous cholecystitis (AAC) in the context of primary EBV infection, with a focus on understanding its prevalence, clinical features, and underlying mechanisms. The study also explores EBV infection association with Gilbert syndrome, a condition that potentially exacerbates the clinical picture. Additionally, a case report of an 18-year-old female presenting with AAC and ascites secondary to EBV infection enhances the review. A comprehensive literature review was conducted, analyzing reported cases of AAC secondary to EBV infection. This involved examining patient demographics, clinical presentations, laboratory findings, and outcomes. The search yielded 44 cases, predominantly affecting young females. Common clinical features included fever, cervical lymphadenopathy, tonsillitis/pharyngitis, and splenomegaly. Laboratory findings highlighted significant hepatic involvement. The review also noted a potential link between AAC in EBV infection and Gilbert syndrome, particularly in cases with abnormal bilirubin levels. AAC is a rare but significant complication of primary EBV infection, primarily observed in young females, and may be associated with Gilbert syndrome. This comprehensive review underscores the need for heightened clinical awareness and timely diagnosis to manage this complication effectively. |
