Film-Forming, Moisturizing, and Sensory Properties of a Cosmetic Formulation Containing Tara Gum and Brazilian Berry Extracts.

Autor: Maia Campos PMBG; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida Do Café, S/nº, Monte Alegre, Ribeirão Preto, SP, Brazil. pmcampos@usp.br., Kakuda L; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida Do Café, S/nº, Monte Alegre, Ribeirão Preto, SP, Brazil., Souza CRF; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida Do Café, S/nº, Monte Alegre, Ribeirão Preto, SP, Brazil.
Jazyk: angličtina
Zdroj: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Mar 27; Vol. 25 (4), pp. 71. Date of Electronic Publication: 2024 Mar 27.
DOI: 10.1208/s12249-024-02790-1
Abstrakt: The development of cosmetic formulations with moisturizing and film-forming properties has been very important to help keep skin physiology and protection. In this context, this study aimed to develop a cosmetic formulation containing Tara gum and Brazilian berry extract and evaluate its physical-mechanical, film-forming, and sensory properties. A gel formulation was developed based on Tara gum added to Plinia cauliflora extract and was characterized by its spreadability profile and sensory properties. A clinical study was carried out with ten participants to evaluate the skin microrelief, stratum corneum water content, transepidermal water loss (TEWL), and skin morphological characteristics by reflectance confocal microscopy (RCM) before and after 2 h of application of the formulations. The formulation with Brazilian berry significantly decreased the work of shear parameter, which can be correlated with improved spreadability in the sensory analysis. The clinical study showed that both formulations improved skin hydration and reduced the TEWL. The RCM imaging analysis showed the visible film on the skin surface, a decrease in the size of furrows, an increase in the reflectance of the interkeratinocytes, and reflectance of the stratum corneum for both formulations. These results were more pronounced for the formulation containing Brazilian berry. The Tara gum in the gel formulation promoted the formation and visualization of a polymeric net on the stratum corneum surface, demonstrated by the images obtained from RCM. However, the formulation added with the Brazilian berry extract improved the skin microrelief, honeycomb pattern of the epidermis, and skin hydration in deeper layers of the epidermis.
(© 2024. The Author(s), under exclusive licence to American Association of Pharmaceutical Scientists.)
Databáze: MEDLINE
Externí odkaz: