Acute effects of high-intensity exercise on brain mechanical properties and cognitive function.

Autor: McIlvain G; Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA.; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Magoon EM; Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA., Clements RG; Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA., Merritt A; Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA., Hiscox LV; Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK., Schwarb H; Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA., Johnson CL; Department of Biomedical Engineering, University of Delaware, Newark, DE, 19716, USA. clj@udel.edu.
Jazyk: angličtina
Zdroj: Brain imaging and behavior [Brain Imaging Behav] 2024 Aug; Vol. 18 (4), pp. 863-874. Date of Electronic Publication: 2024 Mar 28.
DOI: 10.1007/s11682-024-00873-y
Abstrakt: Previous studies have shown that engagement in even a single session of exercise can improve cognitive performance in the short term. However, the underlying physiological mechanisms contributing to this effect are still being studied. Recently, with improvements to advanced quantitative neuroimaging techniques, brain tissue mechanical properties can be sensitively and noninvasively measured with magnetic resonance elastography (MRE) and regional brain mechanical properties have been shown to reflect individual cognitive performance. Here we assess brain mechanical properties before and immediately after engagement in a high-intensity interval training (HIIT) regimen, as well as one-hour post-exercise. We find that immediately after exercise, subjects in the HIIT group had an average global brain stiffness decrease of 4.2% (p < 0.001), and an average brain damping ratio increase of 3.1% (p = 0.002). In contrast, control participants who did not engage in exercise showed no significant change over time in either stiffness or damping ratio. Changes in brain mechanical properties with exercise appeared to be regionally dependent, with the hippocampus decreasing in stiffness by 10.4%. We also found that one-hour after exercise, brain mechanical properties returned to initial baseline values. The magnitude of changes to brain mechanical properties also correlated with improvements in reaction time on executive control tasks (Eriksen Flanker and Stroop) with exercise. Understanding the neural changes that arise in response to exercise may inform potential mechanisms behind improvements to cognitive performance with acute exercise.
(© 2024. The Author(s).)
Databáze: MEDLINE
Externí odkaz: