Fetoscopic laser coagulation for twin-to-twin transfusion syndrome: a comparison of flexible 1.0/1.2 mm fetoscopes with curved sheaths of 2.7/3.3 mm 2 vs. 2 mm fetoscopic lens technique with sheaths of 6.6/11.3 mm 2 .

Autor:	Tchirikov M; Martin-Luther University Halle-Wittenberg, Halle, Germany., Zühlke A; Clinic of Anesthesiology, Martha-Maria Clinic, Halle-Dölau, Germany., Schlabritz-Lutsevich N; School of Medicine at the Permian Basin, Texas Tech University, Health Sciences Center (TTUHSC), Odessa, TX, USA., Entezami M; Center of Prenatal Diagnostic and Human Genetic Kudamm-199, Berlin, Germany., Seliger G; Martin-Luther University Halle-Wittenberg, Halle, Germany., Bergner M; Martin-Luther University Halle-Wittenberg, Halle, Germany., Li W; EWK, Clinic of Obstetrics and Gynecology, Berlin, Germany., Köninger A; University Clinic of Obstetrics and Gynecology, St. Hedwig, Barmherzige Brüder, Regensburg, Germany., Wienke A; Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther University Halle-Wittenberg, Halle, Germany., Yusupbaev R; Republican Scientific and Practical Medical Center for Obstetrics and Gynecology, Tashkent, Uzbekistan., Ebert AD; Praxis of Obstetrics and Gynecology, Berlin, Germany.
Jazyk:	angličtina
Zdroj:	Journal of perinatal medicine [J Perinat Med] 2024 Mar 28; Vol. 52 (5), pp. 530-537. Date of Electronic Publication: 2024 Mar 28 (Print Publication: 2024).
DOI:	10.1515/jpm-2023-0328
Abstrakt:	Objectives: Fetoscopic laser coagulation of placental anastomoses is usually performed for a treatment of twin-to-twin transfusion syndrome (TTTS). A common complication of fetoscopic laser coagulation for TTTS is preterm preliminary rupture of fetal membranes (PPROM) aggravating the neonatal outcome significantly. However, use of an flexible 1 mm fetoscope with an curved sheath could reduce iatrogenic damage of the amniotic membrane and improve neonatal outcomes after laser treatment. The aim of this study was to compare neonatal outcomes using this flexible fetoscope with curved sheath vs. use of a standard lens technique. Methods: Outcomes were retrospective analyzed after use of a standard lens fetoscope of 2 mm (sheath 6.63 mm ² or 11.27 mm ² for anterior placenta) and a flexible fetoscope of 1 mm or 1.2 mm (sheath 2.65 mm ² or 3.34 mm ² ) in two German centers of fetal surgery, performed during 2006-2019. Results: Neonatal outcome of 247 TTTS patients were analyzed including the rates of double and single fetal survival. The survival of at least one fetus was 97.2 % in the group with the ultrathin technique (n=154) compared to 88.3 % (n=93) in the group with the standard lens fetoscope (p=0.008). Survival of both fetuses was not different between groups (81.0 vs. 75.3 %). The procedure to delivery interval was significantly increased using the ultrathin fetoscope (89.1±35.0 d vs. 71.4±35.4 d, p=0.001) resulting in an increased gestational age at delivery by 11 days on average (231.9±28.1 d vs. 221.1±32.7 d, p=0.012). Conclusions: Fetal survival can be significantly increased following TTTS using flexible fetoscope of 1 mm or 1.2 mm (sheath 2.65 mm ² or 3.34 mm ² ). (© 2024 the author(s), published by De Gruyter, Berlin/Boston.)
Databáze:	MEDLINE
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Fetoscopic laser coagulation for twin-to-twin transfusion syndrome: a comparison of flexible 1.0/1.2 mm fetoscopes with curved sheaths of 2.7/3.3 mm 2 vs. 2 mm fetoscopic lens technique with sheaths of 6.6/11.3 mm 2 .

Fetoscopic laser coagulation for twin-to-twin transfusion syndrome: a comparison of flexible 1.0/1.2 mm fetoscopes with curved sheaths of 2.7/3.3 mm 2 vs. 2 mm fetoscopic lens technique with sheaths of 6.6/11.3 mm 2 .