Osteoporosis management in patients with chronic kidney disease (ERCOS Study): A challenge in nephrological care.

Autor:	Bover J; Servicio de Nefrología, Hospital Universitari Germans Trias i Pujol, REMAR-IGTP Group, Can Ruti Campus, Badalona, Barcelona, Spain. Electronic address: jbover.ics@gencat.cat., Gómez-Alonso C; Unidad de Gestión Clínica de Metabolismo Óseo y Mineral, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., Casado E; Servicio de Reumatología, Hospital Universitari Parc Taulí, Sabadell, Barcelona, Spain., Rodríguez-García M; Unidad de Gestión Clínica de Nefrología, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain., Lloret MJ; Servicio de Nefrología, Fundació Puigvert, Institut d'Investigació Biomèdica Sant Pau (IIB-SANT PAU), Barcelona, Spain., Castro-Alonso C; Servicio de Nefrología, Hospital Universitario Doctor Peset, Fundació per al Foment de la Investigació Sanitària i Biomèdica de la Comunitat Valenciana (FISABIO), Valencia, Spain., Gifre L; Servicio de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain., Henríquez-Palop F; Centro de Diálisis Avericum, Las Palmas, Spain., Prior-Español Á; Servicio de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain., López de la Manzanara V; Servicio de Nefrología, Hospital Clínico San Carlos de Madrid, Madrid, Spain., Láiz AM; Servicio de Reumatología, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain., Martínez-Ferrer À; Servicio de Reumatología, Hospital Universitario Doctor Peset, Valencia, Spain., Torregrosa JV; Servicio de Nefrología, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain., Cigarrán S; Servicio de Nefrología, Hospital Público Da Mariña, Burela, Lugo, Spain., Górriz JL; Servicio de Nefrología, Hospital Clínico Universitario de Valencia, Universidad de Valencia, Valencia, Spain., Montomoli M; Servicio de Nefrología, Hospital Clínico Universitario de Valencia, Universidad de Valencia, Valencia, Spain., Panizo N; Servicio de Nefrología, Hospital Clínico Universitario de Valencia, Universidad de Valencia, Valencia, Spain., Costa E; Servicio de Reumatología, Hospital Universitari Parc Taulí, Sabadell, Barcelona, Spain., Martínez-Laguna D; CAP Sant Martí de Provençals, Barcelona, Spain., Rodríguez M; Servicio de Nefrología, Hospital Universitario Reina Sofía, Córdoba, Spain., Navarro-González JF; Unidad de Investigación y Servicio de Nefrología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Islas Canarias, Spain.
Jazyk:	angličtina
Zdroj:	Nefrologia [Nefrologia (Engl Ed)] 2024 Mar-Apr; Vol. 44 (2), pp. 241-250. Date of Electronic Publication: 2024 Mar 25.
DOI:	10.1016/j.nefroe.2024.03.005
Abstrakt:	Fracture risk assessment in patients with chronic kidney disease (CKD) has been included in the CKD-MBD ("Chronic Kidney Disease-Mineral and Bone Disorders") complex in international and national nephrology guidelines, suggesting for the first time the assessment of bone mineral density (BMD) if the results can influence therapeutic decision-making. However, there is very little information on actual clinical practice in this population. The main objective of the ERCOS (ERC-Osteoporosis) study is to describe the profile of patients with CKD G3-5D with osteoporosis (OP) and/or fragility fractures treated in specialized nephrology, rheumatology and internal medicine clinics in Spain. Fifteen centers participated and 162 patients (mostly women [71.2%] postmenopausal [98.3%]) with a median age of 77 years were included. Mean estimated glomerular filtration rate (eGFR) was 36 mL/min/1.73 m 2 and 38% of the included patients were on dialysis. We highlight the high frequency of prevalent fragility fractures [37.7%), mainly vertebral (52.5%) and hip (24.6%)], the disproportionate history of patients with glomerular disease compared to purely nephrological series (corticosteroids) and undertreatment for fracture prevention, especially in nephrology consultations. This study is an immediate call to action with the dissemination of the new, more proactive, clinical guidelines, and underlines the need to standardize a coordinated and multidisciplinary care/therapeutic approach to these patients in an efficient way to avoid current discrepancies and therapeutic nihilism. (Copyright © 2024. Published by Elsevier España, S.L.U.)
Databáze:	MEDLINE
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