The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial.

Autor: Hossam MA; Department of Endodontics, Faculty of Dentistry, Cairo University, Giza, Egypt., El Baz AA; Department of Endodontics, Faculty of Dentistry, Cairo University, Giza, Egypt., Kwak SW; Department of Conservative Dentistry, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University, Yangsan, Korea., Kim HC; Department of Conservative Dentistry, School of Dentistry, Dental Research Institute, Dental and Life Science Institute, Pusan National University, Yangsan, Korea., Abielhassan MM; Department of Endodontics, Faculty of Dentistry, Cairo University, Giza, Egypt.
Jazyk: angličtina
Zdroj: Australian endodontic journal : the journal of the Australian Society of Endodontology Inc [Aust Endod J] 2024 Aug; Vol. 50 (2), pp. 227-236. Date of Electronic Publication: 2024 Mar 25.
DOI: 10.1111/aej.12839
Abstrakt: The aim of this study was to assess the effect of ibuprofen sustained release (SR) oral premedication on the efficacy of buccal infiltration (BI) with intraoperative and postoperative pain after single-visit root canal treatment. Sixty patients diagnosed with symptomatic irreversible pulpitis and apical periodontitis in mandibular molar were divided into two groups. Group SR received ibuprofen SR 800 mg and group PL received placebo capsule 1 h before 3.6 mL articaine BI injection. Pain was recorded using a modified visual analogue scale and postoperatively at intervals 6, 24 and 48 h. Group SR showed a significantly higher anaesthetic success rate (73.3%) compared to group PL (46.7%) (p < 0.05). Intraoperative and postoperative pain was significantly higher in group PL compared to group SR (p < 0.05). Premedication of ibuprofen SR improved the efficacy of primary BI in mandibular molars with symptomatic irreversible pulpitis and decreased postoperative pain at 6 and 48 h.
(© 2024 Australian Society of Endodontology Inc.)
Databáze: MEDLINE
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