Nano guardians of the heart: A comprehensive investigation into the impact of silver nanoparticles on cardiovascular physiology.

Autor: Alshihri AA; Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia., Khan SU; Department of Biochemistry, Women Medical and Dental College, Khyber Medical University, Abbottabad, 22080, Khyber Pakhtunkhwa, Pakistan., Alissa M; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia. Electronic address: m.alissa@psau.edu.sa., Alnoud MAH; Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA 70112; USA., Shams Ul Hassan S; Department of Natural product chemistry, School of Pharmacy, Shanghai Jiao Tong Unviversity, Shanghai, China., Alghamdi SA; Department of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia., Mushtaq RY; Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia., Albariqi AH; Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia., Almhitheef AI; Medical Laboratory Department, General Administration of Medical Services, Riyadh 11333, Saudi Arabia., Anthony S; Liaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical University Liaoning Provence China. Electronic address: safir.biotechnologist22@gmail.com., Sheirdil RA; Saint Peter Hospital Albany New York, USA., Murshed A; Department of Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, 524000, Zhanjiang, China.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Jun; Vol. 49 (6), pp. 102542. Date of Electronic Publication: 2024 Mar 26.
DOI: 10.1016/j.cpcardiol.2024.102542
Abstrakt: Globally, cardiovascular diseases (CVDs) constitute the leading cause of death at the moment. More effective treatments to combat CVDs are urgently required. Recent advances in nanotechnology have opened the door to new avenues for cardiovascular health treatment. Silver nanotechnology's inherent therapeutic powers and wide-ranging applications have made it the center of focus in recent years. This review aims to analyze the chemical, physical, and biological processes ofproducing AgNPs and determine their potential utility as theranostics. Despite significant advances, the precise mechanism by which AgNPs function in numerous biological systems remains a mystery. We hope that at the end of this review, you will better understand how AgNPs affect the cardiovascular system from the research done thus far. This endeavor thoroughly investigates the possible toxicological effects and risks associated with exposure to AgNPs. The findings shed light on novel applications of these versatile nanomaterials and point the way toward future research directions. Due to a shortage of relevant research, we will limit our attention to AgNPs as they pertain to CVDs. Future research can use this opportunity to investigate the many medical uses of AgNPs. Given their global prevalence, we fully endorse academics' efforts to prioritize nanotechnological techniques in pursuing risk factor targeting for cardiovascular diseases. The critical need for innovative solutions to this widespread health problem is underscored by the fact that this technique may help with the early diagnosis and treatment of CVDs.
Competing Interests: Declaration of competing interest The authors declared that they have no competing interests among them.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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