Diabetic Markers, Five Years after Bariatric Surgery.

Autor: Behrooznia Z; Department of Internal Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Jangjoo A; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Qoorchi Moheb Seraj F; Neurosurgical Department, NeuroVascular Section, Mashhad University of Medical Sciences, Mashhad, Iran., Khadem-Rezaiyan M; Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Zandbaf T; Department of General surgery, School of medicine, Mashhad Azad university of medical sciences, Mashhad, Iran., Hassani S; Endocrine Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Jazyk: angličtina
Zdroj: Middle East journal of digestive diseases [Middle East J Dig Dis] 2023 Oct; Vol. 15 (4), pp. 270-276. Date of Electronic Publication: 2023 Oct 30.
DOI: 10.34172/mejdd.2023.357
Abstrakt: Background: Bariatric surgery delivers substantial weight loss for obese patients with comorbidities like diabetes mellitus. We aimed to investigate the impacts of bariatric surgery on diabetic markers after 5 years of follow-up. Methods: This is a retrospective study on patients with diabetes and a history of bariatric surgery between 2016-2017. The diabetic markers before and 5 years following surgery, including a lipid profile, glucose level, and the required antidiabetic medications, were evaluated. Results: 34 consecutive patients were included, 30 (88.2%) women, with a mean age of 52.71±8.53 years. The majority (65%) of surgeries were Roux-en-Y gastric bypass (RYGB), and the remaining were one anastomosis gastric bypass (OAGB) and sleeve gastrectomy (SG). The serum levels of diabetic markers reduced during follow-up ( P =0.001), except for high-density lipoprotein levels and serum total cholesterol, which increased ( P =0.011, P =0.838). Low-density lipoprotein levels reduced, but it was insignificant ( P =0.194). Surgery types had affected the changes of diabetic markers ( P >0.05). Demand for oral medication was reduced significantly, but insulin injection reduction was not significant ( P =0.006 and P =0.099, respectively). Conclusion: Our study showed favorable bariatric surgery results on patients with diabetes in long-term follow-up. However, dyslipidemia is still a concern.
Competing Interests: Competing Interests The authors declare no conflict of interest related to this work.
(© 2023 Middle East Journal of Digestive Diseases.)
Databáze: MEDLINE
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