Methotrexate toxicity complicating a case of rheumatoid arthritis associated Interstitial Lung Disease: Lessons to learn.

Autor:	Ikrou H; Pulmonology Department, CHR HASSAN II, CHU Souss-Massa, Laboratory LARISS, FMPA, UIZ - Agadir, Morocco., Salek M; Radiology Department, CHR HASSAN 2, CHU SOUSS MASSA, FMPA, Agadir, Morocco., Boustani S; Internal Medicine Department, CHR HASSAN 2, CHU SOUSS MASSA, FMPA, Agadir, Morocco., Bouissar W; Internal Medicine Department, CHR HASSAN 2, CHU SOUSS MASSA, FMPA, Agadir, Morocco., Wakrim S; Radiology Department, CHR HASSAN 2, CHU SOUSS MASSA, FMPA, Agadir, Morocco., Abdala S; Pulmonology Department, CHR HASSAN II, CHU Souss-Massa, Laboratory LARISS, FMPA, UIZ - Agadir, Morocco., Serhane H; Pulmonology Department, CHR HASSAN II, CHU Souss-Massa, Laboratory LARISS, FMPA, UIZ - Agadir, Morocco.
Jazyk:	angličtina
Zdroj:	Radiology case reports [Radiol Case Rep] 2024 Mar 16; Vol. 19 (6), pp. 2218-2223. Date of Electronic Publication: 2024 Mar 16 (Print Publication: 2024).
DOI:	10.1016/j.radcr.2024.02.036
Abstrakt:	Rheumatoid arthritis (RA) is one of the most common types of autoimmune arthritis. It can also involve other organs, including vascular structures, and lungs which are affected in 60% to 80% of cases. Other complications may present as airway infections and drug related pulmonary toxicity. We present the case of 75-year-old male patient of North African decent that was hospitalized initially for chronic dyspnea associated with other systemic manifestations, and in whom we confirmed the diagnosis of Rheumatoid arthritis associated interstitial lung disease. The patient was treated with methotrexate (MTX) and later on, he developed a fatal case of methotrexate related pulmonary toxicity. (© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze:	MEDLINE
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