Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): Broadening the scope of outcome measures.

Autor: García de Jalón E; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Ariz MC; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain., Aquerreta A; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain., Aranguren L; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain., Gutierrez G; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain., Corrales A; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain., Sánchez-Torres AM; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain., Gil-Berrozpe GJ; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain., Peralta V; Mental Health Department, Servicio Navarro de Salud - Osasunbidea, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain., Cuesta MJ; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain; Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain. Electronic address: mcuestaz@navarra.es.
Jazyk: angličtina
Zdroj: Spanish journal of psychiatry and mental health [Span J Psychiatry Ment Health] 2023 Jul-Sep; Vol. 16 (3), pp. 192-203. Date of Electronic Publication: 2022 Jul 16.
DOI: 10.1016/j.rpsm.2022.07.002
Abstrakt: Background: This study compares the effectiveness of a new early intervention service for firstepisode psychosis (FEP) in patients under conventional treatment. Six primary and 10 secondary outcome measures are used to better characterize the comparative effectiveness between two FEP groups.
Methods: This study plans to enroll 250 patients aged 15-55 years with FEP from all inpatient and outpatient mental health services and primary health care from January 2020 until December 2022. The control group will be composed of 130 FEP patients treated in mental health centers in the 2 years prior to the start of PEPsNa (Programa de Primeros Episodios de Psicosis de Navarra). The primary outcome measures are symptomatic remission, functional recovery, personal recovery, cognitive performance, functional capacity in real-world settings, and costs. The secondary outcome measures are duration of untreated psychosis, substance abuse rate, antipsychotic monotherapy, minimal effective dose of antipsychotic drugs, therapeutic alliance, drop-out rate, number of relapses, global mortality and suicidality, resource use, and general satisfaction in the program.
Discussion: This study arises from the growing need to broaden the scope of outcome measures in FEP patients and to account for unmet needs of recovery for FEPs. It aims to contribute in the dissemination of the NAVIGATE model in Europe and to provide new evidence of the effectiveness of early intervention services for stakeholders of the National Health Service.
(Copyright © 2022 Sociedad Española de Psiquiatría y Salud Mental (SEPSM). Published by Elsevier España S.L.U. All rights reserved.)
Databáze: MEDLINE
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