Exploring the Prevalence and Characteristics of Obstructive Sleep Apnea Among Idiopathic Pulmonary Fibrosis Patients: A Systematic Review and Meta-Analysis.
| Autor: | Wei CR; Research and Development, Shing Huei Group, Taipei, TWN., Jalali I; Medicine, Tehran University of Medical Sciences, Tehran, IRN., Singh J; Internal Medicine, Adesh Institute of Medical Sciences and Research, Bathinda, IND., Nagaraj A; Surgery, Pharmacology, Our Lady of Fatima University, Bangalore, IND., Dari MA; Otolaryngology-Head and Neck Surgery, Addis Ababa University, Addis Ababa, ETH., Mekonen Gdey M; General Practice, Mekelle University, Mek'ele, ETH., Bai M; Obstetrics and Gynaecology, Shaikh Zaid Women Hospital, Larkana, PAK., Palleti SK; Nephrology, Louisiana State University Health Sciences Center, Shreveport, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Feb 20; Vol. 16 (2), pp. e54562. Date of Electronic Publication: 2024 Feb 20 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.54562 |
| Abstrakt: | The aim of this meta-analysis was to scrutinize the prevalence, characteristics, and outcomes of obstructive sleep apnea (OSA) in individuals with ideopathic pulmonary fibrosis (IPF). We carried out this systematic review and meta-analysis in accordance with the guidelines outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Statement (PRISMA). Two independent researchers systematically searched major databases, including MEDLINE/PubMed, EMBASE, and the Cochrane Library, from January 1, 2000, until December 31, 2023. We included all studies involving adult patients (age >18 years) with IPF that assessed the prevalence and characteristics of OSA in IPF patients. A total of seven studies involving a pooled sample of 411 patients were included in this meta-analysis. The pooled prevalence of OSA among individuals with IPF was found to be 70% (95% CI: 59 to 82%). Individuals with OSA exhibited a significantly higher mean body mass index (BMI) compared to their counterparts. While individuals with both IPF and OSA exhibited higher scores on the Epworth Sleepiness Scale (ESS) compared to those with IPF alone, the OSA group also showed lower oxygen saturation during sleep in comparison to non-OSA patients. In summary, OSA is a prevalent coexisting condition among individuals with IPF. This presence could worsen the nighttime oxygen saturation. Consequently, there is a need for more extensive studies involving more uniform participant groups. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Wei et al.) |
| Databáze: | MEDLINE |
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