Brochure intervention to manage bothersome taste changes in pediatric patients receiving cancer therapy.

Autor: Hassan H; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.; Department of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada., Oloyede S; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada., Villanueva G; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada., Zahra S; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada., Joseph-Frederick Z; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada., Green G; Department of Clinical Dietetics, The Hospital for Sick Children, Toronto, Ontario, Canada., Schechter T; Department of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada., Zupanec S; Department of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada., Dupuis LL; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.; Department of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto., Sung L; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.; Department of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Jun; Vol. 71 (6), pp. e30965. Date of Electronic Publication: 2024 Mar 21.
DOI: 10.1002/pbc.30965
Abstrakt: Background: Primary objective was to determine if a patient informational brochure describing potentially useful strategies could help manage specific taste changes. Secondary objective was to describe the specific strategies used and whether the strategies were perceived as being helpful.
Procedure: This single-center study included pediatric patients with cancer or hematopoietic cell transplant recipients receiving active treatment who experienced bothersome taste changes in the last month. Participants participated in baseline and follow-up interviews conducted 14-21 days apart. A brochure that listed 16 potentially helpful strategies was provided at baseline. At follow-up, we asked about brochure use and whether it helped. At both interviews, we asked about experienced taste changes, strategies used, and whether strategy helped.
Results: Of 100 enrolled participants, different (87%) and bad (72%) taste were most common at baseline. Following the brochure intervention, statistically significant reductions were observed in food tasting different, bad, bland, bitter, sour, and metallic. For most strategies, the proportion of patients who used specific strategies or found them helpful was not significantly different between baseline and follow-up. However, "eating foods you like" was considered helpful in significantly more participants who used the strategy in follow-up (72 out of 89, 80.9%) compared with baseline (55 out of 95, 57.9%; p = .008). Between visits, 81.2% looked at the brochure. Among participants, 53.1% found the brochure helpful, very helpful, or extremely helpful.
Conclusions: A brochure that offered strategies to manage changes in taste helped participants cope with them. Further research should evaluate the brochure using randomized and multicenter trials.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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