| Autor: |
Qiu JM; Department of Preventive Medicine, School of Basic Medicine and Public Health, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China., Zeng FF; Department of Preventive Medicine, School of Basic Medicine and Public Health, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China., Cheng C; Department of Medical Affairs, the First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital), Guangzhou 510630, China., Wen HY; Department of Preventive Medicine, School of Basic Medicine and Public Health, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China., Huang SQ; Department of Preventive Medicine, School of Basic Medicine and Public Health, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China., Liu D; Department of Preventive Medicine, School of Basic Medicine and Public Health, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China., Qi JL; National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Yin P; National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Zhou MG; National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China., Xu Y; Chronic Disease Prevention and Control Hospital of Bao'an District, Shenzhen 518020, China., Liu ZP; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou 511436, China., Mei QS; Department of Medical Biochemistry and Molecular Biology, School of Basic Medical and Public Health, Jinan University, Guangzhou 510632, China., Xiao H; School of Life Science and Technology/Research Institute of Pathogenic Microorganisms, Jinan University, Guangzhou 510632,China., Xiang Z; Department of Microbiology and Immunology, School of Basic Medicine and Public Health, Jinan University, Guangzhou 510632, China., Liang XF; Department of Preventive Medicine, School of Basic Medicine and Public Health, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China. |
| Abstrakt: |
Objective: To examine the burden and trends of acute viral hepatitis in Guangdong Province from 1990 to 2019, and provide reference evidences for hepatitis prevention and control in the province. Methods: Data on acute viral hepatitis (hepatitis A, B, C, and E) in Guangdong from 1990 to 2019 were extracted from the Global Burden of Disease Study 2019 database. The incidence, prevalence, mortality, and disability-adjusted life years (DALY) data were analyzed by age and gender, and the estimated annual percentage change (EAPC) was calculated to describe the changing trends in disease burden. Results: From 1999 to 2019, the standardized incidence, prevalence, mortality, and DALY of acute viral hepatitis in Guangdong were higher than the national averages. In 2019, 51.43% (2 245 087/4 365 221) of acute viral hepatitis cases in Guangdong Province were mainly attributed to hepatitis B, and 77.18% (106/138) of deaths were due to acute hepatitis B. In different age groups, except for acute hepatitis B, which was more common in adults, the incidence rates of other types of viral hepatitis such as hepatitis A, B, and E showed an overall decreasing trend with age. The mortality rates of different types of acute viral hepatitis, except for the <5 age group, increased with age. The overall incidence and mortality rates of acute viral hepatitis were higher in men than in women. Conclusions: The overall burden of acute viral hepatitis in Guangdong declined in 2019, but remained higher than the national level. Further efforts are needed to strengthen hepatitis prevention and screening in different population in Guangdong Province, especially in children and the elderly. |
