Performance Differences of a Touch-Based Serial Reaction Time Task in Healthy Older Participants and Older Participants With Cognitive Impairment on a Tablet: Experimental Study.
| Autor: | Mychajliw C; Geriatric Center, University Hospital for Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.; TuCAN, Tübingen Cognitive Assessment for Neuropsychiatric Disorders, Tübingen, Germany., Holz H; TuCAN, Tübingen Cognitive Assessment for Neuropsychiatric Disorders, Tübingen, Germany.; Institute of Computer Science, Ludwigsburg University of Education, Ludwigsburg, Germany.; LEAD Graduate School & Research Network, University of Tübingen, Tübingen, Germany., Minuth N; Geriatric Center, University Hospital for Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.; TuCAN, Tübingen Cognitive Assessment for Neuropsychiatric Disorders, Tübingen, Germany., Dawidowsky K; Geriatric Center, University Hospital for Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.; TuCAN, Tübingen Cognitive Assessment for Neuropsychiatric Disorders, Tübingen, Germany., Eschweiler GW; Geriatric Center, University Hospital for Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Metzger FG; Geriatric Center, University Hospital for Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.; Vitos Hospital for Psychiatry and Psychotherapy Haina, Klinik für Psychiatrie und Psychotherapie, Vitos Haina gGmbH, Haina, Germany., Wortha F; TuCAN, Tübingen Cognitive Assessment for Neuropsychiatric Disorders, Tübingen, Germany.; LEAD Graduate School & Research Network, University of Tübingen, Tübingen, Germany.; Centre for Early Mathematics Learning, School of Science, Loughborough University, Loughborough, United Kingdom. |
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| Jazyk: | angličtina |
| Zdroj: | JMIR aging [JMIR Aging] 2024 Mar 21; Vol. 7, pp. e48265. Date of Electronic Publication: 2024 Mar 21. |
| DOI: | 10.2196/48265 |
| Abstrakt: | Background: Digital neuropsychological tools for diagnosing neurodegenerative diseases in the older population are becoming more relevant and widely adopted because of their diagnostic capabilities. In this context, explicit memory is mainly examined. The assessment of implicit memory occurs to a lesser extent. A common measure for this assessment is the serial reaction time task (SRTT). Objective: This study aims to develop and empirically test a digital tablet-based SRTT in older participants with cognitive impairment (CoI) and healthy control (HC) participants. On the basis of the parameters of response accuracy, reaction time, and learning curve, we measure implicit learning and compare the HC and CoI groups. Methods: A total of 45 individuals (n=27, 60% HCs and n=18, 40% participants with CoI-diagnosed by an interdisciplinary team) completed a tablet-based SRTT. They were presented with 4 blocks of stimuli in sequence and a fifth block that consisted of stimuli appearing in random order. Statistical and machine learning modeling approaches were used to investigate how healthy individuals and individuals with CoI differed in their task performance and implicit learning. Results: Linear mixed-effects models showed that individuals with CoI had significantly higher error rates (b=-3.64, SE 0.86; z=-4.25; P<.001); higher reaction times (F Conclusions: Our results showed that the HC and CoI groups differed substantially in their performance in the SRTT. This highlights the promising potential of implicit learning paradigms in the detection of CoI. The short testing paradigm based on these results is easy to use in clinical practice. (©Christian Mychajliw, Heiko Holz, Nathalie Minuth, Kristina Dawidowsky, Gerhard Wilhelm Eschweiler, Florian Gerhard Metzger, Franz Wortha. Originally published in JMIR Aging (https://aging.jmir.org), 21.03.2024.) |
| Databáze: | MEDLINE |
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