Kikuchi-Fujimoto disease during early pregnancy.

Autor: Ichikawa G; Department of Obstetrics and Gynecology, Nippon Medical School, Tokyo, Japan.; Department of Obstetrics and Gynecology, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan., Negishi Y; Department of Obstetrics and Gynecology, Nippon Medical School, Tokyo, Japan.; Department of Microbiology and Immunology, Nippon Medical School, Tokyo, Japan., Chishima F; Department of Obstetrics and Gynecology, Kawaguchi Municipal Medical Center, Saitama, Japan.; Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan., Suzuki S; Department of Obstetrics and Gynecology, Nippon Medical School, Tokyo, Japan.
Jazyk: angličtina
Zdroj: The journal of obstetrics and gynaecology research [J Obstet Gynaecol Res] 2024 Jun; Vol. 50 (6), pp. 1056-1060. Date of Electronic Publication: 2024 Mar 21.
DOI: 10.1111/jog.15928
Abstrakt: Kikuchi-Fujimoto disease (KFD) is rare during pregnancy. It is characterized by necrotizing lymphadenitis and often occurs in young Asian women. We report a case of KFD during pregnancy, which was difficult to diagnose. A 37-year-old pregnant female (gestational week [GW] 7 +5 ) was admitted to our hospital because of hyperemesis gravidarum. On the eighth day of hospitalization (GW 8 +6 ), she suddenly developed a fever (38.0°C) with skin rash and posterior pharynx redness. Blood tests showed pancytopenia and abnormal liver function. The patient was misdiagnosed with severe Epstein-Barr virus infection and administered with prednisolone. Subsequently, cervical lymphadenopathy was observed, and biopsy results led to the diagnosis of KFD. Thereafter, her symptoms improved, and she was discharged at GW 13 +4 . KFD must be included as a differential diagnosis for patients with fever, abnormal liver function, and pancytopenia during pregnancy.
(© 2024 The Authors. Journal of Obstetrics and Gynaecology Research published by John Wiley & Sons Australia, Ltd on behalf of Japan Society of Obstetrics and Gynecology.)
Databáze: MEDLINE
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