Sustained Relief of Complex Regional Pain Syndrome (CRPS) Pain Following a 60-Day Peripheral Nerve Stimulation: A Report of Three Cases.

Autor: Gutierrez GJ; Pain Management, Pain Specialists of America, Austin, USA., Zurn CA; Research and Development, SPR Therapeutics, Cleveland, USA., Crosby ND; Research and Development, SPR Therapeutics, Cleveland, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Feb 19; Vol. 16 (2), pp. e54458. Date of Electronic Publication: 2024 Feb 19 (Print Publication: 2024).
DOI: 10.7759/cureus.54458
Abstrakt: Patients who present to pain clinics with complex regional pain syndrome (CRPS) typically have debilitating pain, including hyperalgesia and allodynia, and additional substantial quality-of-life concerns related to the motor and autonomic-related symptoms of CRPS. Present treatments for CRPS such as neuropathic pain medications and sympathetic blocks are often unsatisfactory for managing symptoms. The present cases highlight the use of a 60-day percutaneous peripheral nerve stimulation (PNS) treatment for three patients with CRPS Type I affecting the foot. In all three patients, the tibial and common peroneal nerves were targeted separately at the popliteal fossa with two percutaneous leads each placed a remote distance (~1 cm) from the target nerve under ultrasound guidance. All three patients reported substantial pain relief and resolution of autonomic symptoms (e.g., swelling, edema, erythema), with sustained relief lasting 8-10 months in two patients, and 34 months (as of this writing) in the third patient. There were no medical complications. These three cases suggest that 60-day PNS is a safe and efficacious treatment for CRPS.
Competing Interests: Claire A. Zurn and Nathan D. Crosby are co-inventors on patents related to the technology described in this work.
(Copyright © 2024, Gutierrez et al.)
Databáze: MEDLINE