Intravenous Hydration and Associated Outcomes in Patients With Sickle Cell Disease Admitted With Vaso-Occlusive Crises: A Systematic Review.

Autor:	Pandey S; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Tan EFS; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Bellamkonda A; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Aryal B; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Karki S; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Boddu G; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Sapkota R; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Changela M; Internal Medicine, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA., Kalavar M; Hematology and Oncology, One Brooklyn Health System/Interfaith Medical Center, Brooklyn, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Feb 19; Vol. 16 (2), pp. e54463. Date of Electronic Publication: 2024 Feb 19 (Print Publication: 2024).
DOI:	10.7759/cureus.54463
Abstrakt:	Acute painful vaso-occlusive crisis (VOC) is the common presentation of sickle cell disease (SCD) leading to emergency room visits, admissions, morbidity, mortality, and negative impacts on quality of life. Among various treatment approaches commonly employed to manage the condition, intravenous (IV) hydration is also frequently used in emergency and inpatient settings. Although helpful to overcome dehydration, IV hydration often leads to adverse outcomes like fluid overload, pulmonary edema, increased length of stay, transfer to intensive care unit, new oxygen requirement, etc. Small-scale retrospective studies are conducted to study the outcomes of IV hydration but have failed to conclusively demonstrate its benefits as well as choice of IV fluids, rate of IV fluid replacement, etc. We conduct this review as an attempt to summarize the available evidence on the role and utility of IV hydration in sickle cell crises along with reported adverse outcomes. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Pandey et al.)
Databáze:	MEDLINE
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