Cerebral tumor with hemi-dural enhancement as unique presentation of multiple myeloma: A case report.

Autor:	van Lanen RHGJ; Department of Neurosurgery, Maastricht University Medical Centre+, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands., Huijs SMH; Department of Neurology, Maastricht University Medical Centre+, Maastricht, the Netherlands., Postma AA; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.; Department of Radiology, Maastricht University Medical Centre+, Maastricht, the Netherlands., Haeren RHL; Department of Neurosurgery, Maastricht University Medical Centre+, Maastricht, the Netherlands.; School for Mental Health and Neuroscience (MHeNs), Maastricht University, Maastricht, the Netherlands.
Jazyk:	angličtina
Zdroj:	Brain & spine [Brain Spine] 2023 Dec 20; Vol. 4, pp. 102730. Date of Electronic Publication: 2023 Dec 20 (Print Publication: 2024).
DOI:	10.1016/j.bas.2023.102730
Abstrakt:	Introduction: Intracranial multiple myeloma (MM) is a rare manifestation of MM, a malignant plasma cell disorder that primarily affects bone marrow. Dural involvement in MM is even rarer and can manifest as a dural mass. We present a case of MM presenting as an intracranial dural tumor with primary hemi-dural involvement. Research Question: This case report aims to investigate the clinical presentation, diagnostic challenges, and treatment approaches for intracranial multiple myeloma, with a focus on the extensive hemi-dural thickening and enhancement seen in this case. Material and Methods: A 73-year-old male presented with progressive dysphasia and weakness. MRI revealed a solid left frontal mass with significant mass-effect. Hemi-dural thickening and enhancement was present along with invasion of the skull. The patient underwent surgical resection of the tumor with dural and bone reconstruction. Results: Histopathological examination confirmed MM diagnosis. Chemotherapy was started. Follow-up MRI showed complete tumor resection, but extensive hemi-dural thickening and enhancement persisted. Postoperative radiation therapy was considered. Discussion and Conclusion: MM with primary dural involvement is rare and poses diagnostic challenges. Postoperative treatment involves chemotherapy, the role of surgery and radiotherapy is not established. The extensive hemi-dural thickening and enhancement observed in this case require further investigation, and a wait-and-scan policy was recommended instead of radiotherapy. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Authors.)
Databáze:	MEDLINE
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