Syphilitic ostial coronary artery occlusion treated with percutaneous coronary intervention: Case series and literature review.

Autor:	Baydoun Y; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America., Stukov Y; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America.; M. M. Amosov National Institute of Cardiovascular Surgery, The National Academy of the Medical Sciences of Ukraine, Kyiv, Ukraine.; Center for Regenerative Medicine, Division of Cardiovascular Medicine, Department of Medicine, University of Florida, Gainesville, FL, United States of America., Purlee MS; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America., Chagnon B; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America., Salo SV; M. M. Amosov National Institute of Cardiovascular Surgery, The National Academy of the Medical Sciences of Ukraine, Kyiv, Ukraine., Gavrylyshin AY; M. M. Amosov National Institute of Cardiovascular Surgery, The National Academy of the Medical Sciences of Ukraine, Kyiv, Ukraine., Lazoryshynets V; M. M. Amosov National Institute of Cardiovascular Surgery, The National Academy of the Medical Sciences of Ukraine, Kyiv, Ukraine., Levchyshyna O; M. M. Amosov National Institute of Cardiovascular Surgery, The National Academy of the Medical Sciences of Ukraine, Kyiv, Ukraine., Sharaf OM; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America., Peek GJ; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America., Bleiweis MS; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America., Jacobs JP; Congenital Heart Center, Division of Cardiovascular Surgery, Departments of Surgery and Pediatrics, University of Florida, Gainesville, FL, United States of America.
Jazyk:	angličtina
Zdroj:	American heart journal plus : cardiology research and practice [Am Heart J Plus] 2023 Oct 21; Vol. 36, pp. 100337. Date of Electronic Publication: 2023 Oct 21 (Print Publication: 2023).
DOI:	10.1016/j.ahjo.2023.100337
Abstrakt:	Introduction: Non-atherosclerotic causes of acute coronary syndrome (ACS) are important contributors to a substantial number of acute ischemic coronary events. Syphilitic aortitis is a rare complication of tertiary cardiovascular syphilis that may result in ostial coronary artery stenosis, aortic insufficiency, and ascending aortic aneurysm. Methods: In this manuscript, we present two Case Reports of patients with bilateral syphilitic coronary artery ostial occlusion, and we review the associated literature. The immunofluorescent test was positive for syphilis in both patients. Results: Diagnostic coronary angiography revealed bilateral occlusions of the left main coronary artery (LMCA) and right coronary artery (RCA), which were successfully treated with percutaneous coronary intervention (PCI) with bare metal stents (BMS). After deployment of the stents, arterial blood flow was re-established with TIMI flow grade 3. Discussion: The angiographic finding of bilateral coronary ostial lesions in young patients should raise the suspicion of cardiovascular syphilis. Options for revascularization should be discussed amongst the patient and the Heart Team. PCI may be an option for treatment of isolated syphilitic coronary stenosis in the setting of acute hemodynamic instability or chronic inflammation. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Authors.)
Databáze:	MEDLINE
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