Mortality Factors in Crush Syndrome.

Autor: Onan E; Department of Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Torun D; Department of Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Kozanoğlu R; Department of Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Miçözkadıoğlu H; Department of Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Beyaz S; Department of Orthopaedics and Traumatology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Özgözen L; Department of Orthopaedics and Traumatology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Turgut N; Department of Orthopaedics and Traumatology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Demiroğlu YZ; Department of Clinical Microbiology and Infectious Diseases, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Karagün Ö; Department of Emergency Medicine, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Ergenoğlu P; Department of Intensive Care Medicine, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Kuşçu ÖÖ; Department of Intensive Care Medicine, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Altan E; Department of Gastroenterology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Güven AT; Department of Internal Medicine, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Abdullayev A; Department of Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Karluka İ; Department of Radiology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Yalçın Ç; Department of Radiology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Mazıcan M; Department of Radiology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Balcı İG; Department of Radiology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Özkan B; Department of Plastic and Reconstructive Surgery, Baskent University, Ankara-Türkiye., Parmaksız G; Department of Pediatric Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Avcı B; Department of Pediatric Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Noyan A; Department of Pediatric Nephrology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Çolak T; Department of Nephrology, Baskent University, Ankara-Türkiye., Tünel HA; Department of Cardiovascular Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana, Turkey., Temiz A; Department of Pediatric Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Gezer HÖ; Department of Pediatric Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Erdoğan C; Department of Pediatric Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Bairamoi G; Department of Pediatric Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Yünlüel D; Department of Pediatric Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Çivi S; Department of Neurosurgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Durdağ E; Department of Neurosurgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Kardeş Ö; Department of Neurosurgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Süner Hİ; Department of Neurosurgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Tufan K; Department of Neurosurgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Erkan S; Department of General Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Avcı T; Department of General Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Gündoğdu R; Department of General Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Kuş M; Department of General Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Fındıkçıoğlu A; Department of Thoracic Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Yıldız O; Department of Thoracic Surgery, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Alışkan E; Department of Microbiology, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Coşkunoğlu C; Department of Biochemistry, Baskent University Adana Dr. Turgut Noyan Traning and Research Hospital, Adana-Türkiye., Haberal M; Department of Transplantation, Baskent University, Ankara-Türkiye.
Jazyk: angličtina
Zdroj: Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2024 Mar; Vol. 30 (3), pp. 174-184.
DOI: 10.14744/tjtes.2024.20532
Abstrakt: Background: Crush Syndrome is a major cause of morbidity and mortality following large-scale catastrophic earthquakes. Since there are no randomized controlled studies on Crush Syndrome, knowledge on this subject is limited to expert experience. The primary objective is to analyze the epidemiological and demographic characteristics, clinical outcomes, and mortality factors of earthquake victims after the Pazarcik and Elbistan earthquakes on February 6, 2023.
Methods: This cross-sectional and observational retrospective study evaluated 610 earthquake victims who presented to our center between February 6 and April 30, 2023. Among these patients, 128 with Crush Syndrome were included in the study. Patient information was gathered from hospital records during their stay and from national registries upon referral. The primary outcome was to identify risk factors for mortality. Demographic and laboratory data were analyzed by acute kidney injury (AKI) stages; mortality-affecting factors were identified through regression analysis.
Results: Of the 128 Crush Syndrome patients (100 adults, 28 children), 64 were female. The AKI rate was 32.8%. Among patients with AKI, the frequency of hemodialysis requirement was 69%, and the mortality rate was 14.2%. The overall mortality rate for patients with Crush Syndrome was 4.6%, compared to 3.9% (19/482) in earthquake victims without Crush Syndrome (p=0.705). Notably, low systolic blood pressure at admission was the only factor significantly affecting mortality in Crush Syndrome patients (Hazard Ratio [HR]: 1.088, p=0.021, 95% Confidence Interval [CI]).
Conclusion: Our study highlights low systolic blood pressure upon admission as a significant risk factor for increased mortality in Crush Syndrome patients. This finding may contribute to the literature by emphasizing the importance of monitoring blood pressure under rubble and administering more aggressive fluid therapy to patients with low systolic blood pressure.
Databáze: MEDLINE