Applying genetic technologies to combat infectious diseases in aquaculture.

Autor: Robinson NA; Nofima AS Tromsø Norway.; Sustainable Aquaculture Laboratory-Temperate and Tropical (SALTT) School of BioSciences, The University of Melbourne Melbourne Victoria Australia., Robledo D; The Roslin Institute and Royal (Dick) School of Veterinary Studies The University of Edinburgh Edinburgh UK., Sveen L; Nofima AS Tromsø Norway., Daniels RR; The Roslin Institute and Royal (Dick) School of Veterinary Studies The University of Edinburgh Edinburgh UK., Krasnov A; Nofima AS Tromsø Norway., Coates A; Sustainable Aquaculture Laboratory-Temperate and Tropical (SALTT) School of BioSciences, The University of Melbourne Melbourne Victoria Australia., Jin YH; The Roslin Institute and Royal (Dick) School of Veterinary Studies The University of Edinburgh Edinburgh UK., Barrett LT; Sustainable Aquaculture Laboratory-Temperate and Tropical (SALTT) School of BioSciences, The University of Melbourne Melbourne Victoria Australia.; Institute of Marine Research, Matre Research Station Matredal Norway., Lillehammer M; Nofima AS Tromsø Norway., Kettunen AH; Nofima AS Tromsø Norway., Phillips BL; Sustainable Aquaculture Laboratory-Temperate and Tropical (SALTT) School of BioSciences, The University of Melbourne Melbourne Victoria Australia., Dempster T; Sustainable Aquaculture Laboratory-Temperate and Tropical (SALTT) School of BioSciences, The University of Melbourne Melbourne Victoria Australia., Doeschl-Wilson A; The Roslin Institute and Royal (Dick) School of Veterinary Studies The University of Edinburgh Edinburgh UK., Samsing F; Sydney School of Veterinary Science The University of Sydney Camden Australia., Difford G; Nofima AS Tromsø Norway., Salisbury S; The Roslin Institute and Royal (Dick) School of Veterinary Studies The University of Edinburgh Edinburgh UK., Gjerde B; Nofima AS Tromsø Norway., Haugen JE; Nofima AS Tromsø Norway., Burgerhout E; Nofima AS Tromsø Norway., Dagnachew BS; Nofima AS Tromsø Norway., Kurian D; The Roslin Institute and Royal (Dick) School of Veterinary Studies The University of Edinburgh Edinburgh UK., Fast MD; Atlantic Veterinary College The University of Prince Edward Island Charlottetown Prince Edward Island Canada., Rye M; Benchmark Genetics Bergen Norway., Salazar M; Benchmark Genetics Bergen Norway., Bron JE; Institute of Aquaculture University of Stirling Stirling Scotland UK., Monaghan SJ; Institute of Aquaculture University of Stirling Stirling Scotland UK., Jacq C; Blue Analytics, Kong Christian Frederiks Plass 3 Bergen Norway., Birkett M; Rothamsted Research Hertfordshire UK., Browman HI; Institute of Marine Research, Austevoll Research Station, Ecosystem Acoustics Group Tromsø Norway., Skiftesvik AB; Institute of Marine Research, Austevoll Research Station, Ecosystem Acoustics Group Tromsø Norway., Fields DM; Bigelow Laboratory for Ocean Sciences Boothbay Maine USA., Selander E; Department of Marine Sciences University of Gothenburg Gothenburg Sweden., Bui S; Institute of Marine Research, Matre Research Station Matredal Norway., Sonesson A; Nofima AS Tromsø Norway., Skugor S; Cargill Aqua Nutrition Bergen Norway., Østbye TK; Nofima AS Tromsø Norway., Houston RD; Benchmark Genetics Bergen Norway.
Jazyk: angličtina
Zdroj: Reviews in aquaculture [Rev Aquac] 2023 Mar; Vol. 15 (2), pp. 491-535. Date of Electronic Publication: 2022 Sep 05.
DOI: 10.1111/raq.12733
Abstrakt: Disease and parasitism cause major welfare, environmental and economic concerns for global aquaculture. In this review, we examine the status and potential of technologies that exploit genetic variation in host resistance to tackle this problem. We argue that there is an urgent need to improve understanding of the genetic mechanisms involved, leading to the development of tools that can be applied to boost host resistance and reduce the disease burden. We draw on two pressing global disease problems as case studies-sea lice infestations in salmonids and white spot syndrome in shrimp. We review how the latest genetic technologies can be capitalised upon to determine the mechanisms underlying inter- and intra-species variation in pathogen/parasite resistance, and how the derived knowledge could be applied to boost disease resistance using selective breeding, gene editing and/or with targeted feed treatments and vaccines. Gene editing brings novel opportunities, but also implementation and dissemination challenges, and necessitates new protocols to integrate the technology into aquaculture breeding programmes. There is also an ongoing need to minimise risks of disease agents evolving to overcome genetic improvements to host resistance, and insights from epidemiological and evolutionary models of pathogen infestation in wild and cultured host populations are explored. Ethical issues around the different approaches for achieving genetic resistance are discussed. Application of genetic technologies and approaches has potential to improve fundamental knowledge of mechanisms affecting genetic resistance and provide effective pathways for implementation that could lead to more resistant aquaculture stocks, transforming global aquaculture.
(© 2022 The Authors. Reviews in Aquaculture published by John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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