Effects of aging on attachment of Candida albicans to conventional heat-polymerized, CAD-CAM milled, and CAD-CAM 3D-printed acrylic resin bases.

Autor: Jung GK; Department of Prosthodontics, Naval Postgraduate Dental School, Bethesda, Maryland, USA.; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Navy Medicine Readiness & Training Command, Camp Pendleton, California, USA., Mora SN; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; 3D Dental Battalion, US Naval Dental Center, Okinawa, Japan.; Department of Comprehensive Dentistry, Naval Postgraduate Dental School, Bethesda, Maryland, USA., Yune SS; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Comprehensive Dentistry, Naval Postgraduate Dental School, Bethesda, Maryland, USA., Petrich A; Department of Prosthodontics, Naval Postgraduate Dental School, Bethesda, Maryland, USA.; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Hernandez-Feldpausch M; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Comprehensive Dentistry, Naval Postgraduate Dental School, Bethesda, Maryland, USA., Hamlin CM; Department of Prosthodontics, Naval Postgraduate Dental School, Bethesda, Maryland, USA.; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Tuamokumo FO; Department of Research Programs, Walter Reed National Military Medical Center, Bethesda, Maryland, USA., Kim JJ; Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Research, Naval Postgraduate Dental School, Bethesda, Maryland, USA.
Jazyk: angličtina
Zdroj: Journal of prosthodontics : official journal of the American College of Prosthodontists [J Prosthodont] 2024 Mar 19. Date of Electronic Publication: 2024 Mar 19.
DOI: 10.1111/jopr.13844
Abstrakt: Purpose: The aim of this study was to assess Candida albicans attachment on conventionally fabricated (polymethylmethacrylate, PMMA), CAD-CAM milled, and 3D-printed acrylic resin bases pre- and post-simulated thermal aging, along with examining material surface changes after aging.
Materials and Methods: Forty-six samples (10 mm × 10 mm × 2 mm) for each of four material groups (conventional heat-polymerized PMMA, CAD-CAM milled acrylic resin base, CAD-CAM 3D-printed methacrylate resin base, CAD-CAM 3D-printed urethane methacrylate resin base) were subjected to 0, 1, or 2 years of simulated thermal aging. Microscopic images were taken before and after aging, and C. albicans attachment was quantified using cell proliferation assay (XTT). Statistical analysis employed analysis of variance (α = 0.05).
Results: Two-way factorial analysis showed no significant differences based on acrylic resin type or thermal aging (p = 0.344 and p = 0.091 respectively). However, C. albicans attachment significantly differed between 0- and 2-year thermally aged groups (p = 0.004), mainly due to elevated initial attachments on CAD-CAM milled acrylic resin base and CAD-CAM 3D-printed urethane methacrylate resin base.
Conclusions: Regardless of the fabrication technique and material combination, no significant differences were found in C. albicans adhesion pre- or post- thermal aging. Milled and 3D-printed bases compared favorably with heat- polymerized PMMA in their affinity for C. albicans attachment and surface characteristics after aging. These findings indicate that the risk of patients developing denture stomatitis might not be linked to the type of acrylic resin or fabrication method used.
(© 2024 by the American College of Prosthodontists.)
Databáze: MEDLINE
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