| Autor: |
Guo BJ; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China., Sun JH; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China., Pei LX; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China. 11801758@qq.com. |
| Jazyk: |
English; Chinese |
| Zdroj: |
Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2024 Mar 25; Vol. 49 (3), pp. 307-314. |
| DOI: |
10.13702/j.1000-0607.20221428 |
| Abstrakt: |
Oxidative stress is associated with a variety of disease pathologies, it may lead to mitochondrial dysfunction, damage of impaired DNA repairment, cell damage or apoptosis. Acupuncture and moxibustion therapy has been proved to have a role in reducing oxidative stress in organisms under pathological conditions. In the present paper, we collected literatures in both English and Chinese from domestic and foreign databases on the mechanisms of acupuncture and moxibustion underlying amelioration of oxidative stress over the past 5 years, and analyzed the link between acupuncture-moxibustion intervention and redox biology from four aspects： 1) regulation of the production of reactive oxygen species (ROS), 2) affecting antioxidant enzyme-related pathways to reduce ROS, 3) repairing proteins, lipids and DNAs attacked by ROS, and 4) inhibiting downstream apoptosis or autophagy of ROS pathway. By summarizing and prospecting such antioxidant mechanisms, this paper may provide some basis and ideas for in-depth mechanism research on acupuncture and moxibustion to improve oxidative stress and related diseases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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