Translational molecular imaging: Thrombosis imaging with positron emission tomography.

Autor: Balmforth C; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom. Electronic address: Craig.balmforth@ed.ac.uk., Whittington B; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom., Tzolos E; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom., Bing R; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom., Williams MC; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging, Queen's Medical Research Institute, Edinburgh, United Kingdom., Clark L; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom., Corral CA; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging, Queen's Medical Research Institute, Edinburgh, United Kingdom., Tavares A; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging, Queen's Medical Research Institute, Edinburgh, United Kingdom., Dweck MR; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom., Newby DE; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Jazyk: angličtina
Zdroj: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2024 Sep; Vol. 39, pp. 101848. Date of Electronic Publication: 2024 Mar 16.
DOI: 10.1016/j.nuclcard.2024.101848
Abstrakt: A key focus of cardiovascular medicine is the detection, treatment, and prevention of disease, with a move towards more personalized and patient-centred treatments. To achieve this goal, novel imaging approaches that allow for early and accurate detection of disease and risk stratification are needed. At present, the diagnosis, monitoring, and prognostication of thrombotic cardiovascular diseases are based on imaging techniques that measure changes in structural anatomy and biological function. Molecular imaging is emerging as a new tool for the non-invasive detection of biological processes, such as thrombosis, that can improve identification of these events above and beyond current imaging modalities. At the forefront of these evolving techniques is the use of high-sensitivity radiotracers in conjunction with positron emission tomography imaging that could revolutionise current diagnostic paradigms by improving our understanding of the role and origin of thrombosis in a range of cardiovascular diseases.
(Crown Copyright © 2024. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE