One-year follow-up of COVID-19 recoverees with impaired pulmonary function: A prospective cohort study.

Autor: Epstein NK; Infectious Diseases Unit, Meir Medical Center, Kfar-Saba, Israel; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: nitzan.epstein@gmail.com., Yelin D; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Infectious Diseases Unit, Sheba Medical Center, Ramat-Gan, Israel., Shitenberg D; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Pulmonology Unit, Rabin Medical Center, Petach-Tikva, Israel., Yahav D; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Infectious Diseases Unit, Sheba Medical Center, Ramat-Gan, Israel., Leibovici L; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Research Unit, Rabin Medical Center, Petach-Tikva, Israel., Daitch V; Department of Internal Medicine E, Rabin Medical Center, Petach-Tikva, Israel., Margalit I; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Infectious Diseases Unit, Sheba Medical Center, Ramat-Gan, Israel.
Jazyk: angličtina
Zdroj: Infectious diseases now [Infect Dis Now] 2024 Apr; Vol. 54 (3), pp. 104890. Date of Electronic Publication: 2024 Mar 16.
DOI: 10.1016/j.idnow.2024.104890
Abstrakt: Decreased diffusion capacity for carbon monoxide (DLCO) is the most prevalent pulmonary testing abnormality among COVID-19 recoverees. We prospectively followed 51 individuals with impaired DLCO at an average of ∼3 months following COVID-19 and re-examined them at one year. At follow-up, mean DLCO increased from 68.0 % to 72.6 % (p = 0.002); while 33 % of the cohort experienced a clinically significant rise (>10 points) in DLCO, only 29 % normalized their values. While DLCO change did not correlate with symptoms, lack of improvement was more prevalent among individuals with obesity. Regardless of COVID-19 severity, a substantial proportion continued to exhibit DLCO impairment at 1-year.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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