| Autor: |
Ludington WB; Department of Biosphere Sciences and Engineering, Carnegie Institution for Science, Baltimore, MD 21218, USA.; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2024 May 06; Vol. 379 (1901), pp. 20230066. Date of Electronic Publication: 2024 Mar 18. |
| DOI: |
10.1098/rstb.2023.0066 |
| Abstrakt: |
Gut bacteria are prevalent throughout the Metazoa and form complex microbial communities associated with food breakdown, nutrient provision and disease prevention. How hosts acquire and maintain a consistent bacterial flora remains mysterious even in the best-studied animals, including humans, mice, fishes, squid, bugs, worms and flies. This essay visits the evidence that hosts have co-evolved relationships with specific bacteria and that some of these relationships are supported by specialized physical niches that select, sequester and maintain microbial symbionts. Genetics approaches could uncover the mechanisms for recruiting and maintaining the stable and consistent members of the microbiome. This article is part of the theme issue 'Sculpting the microbiome: how host factors determine and respond to microbial colonization'. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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