Hypoparathyroidism Revealed by Unsuccessful Anti-epileptic Therapy.

Autor: Arrab R; Department of Pediatrics, Mohammed VI International University Hospital, Mohammed VI University of Health Sciences (UM6SS), Casablanca, MAR., Benchehab Y; Department of Pediatrics, Mohammed VI International University Hospital, Mohammed VI University of Health Sciences (UM6SS), Casablanca, MAR., Guessous F; Department of Biological Sciences, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, MAR., Dini N; Department of Pediatrics, Mohammed VI University of Health Sciences (UM6SS), Casablanca, MAR.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Feb 14; Vol. 16 (2), pp. e54200. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024).
DOI: 10.7759/cureus.54200
Abstrakt: Pediatric hypoparathyroidism is an uncommon endocrine disease that can be either isolated or syndromic. It occurs when the secretion of parathormone is insufficient to maintain normal levels of ionized calcium. Patients with hypoparathyroidism can exhibit cerebral calcifications and metabolic disorders, and the severity of such features is inversely correlated with hypocalcemia. We report a case of a 13-year-old patient who was initially diagnosed with epilepsy by another medical team two years before her admission to our hospital and who was subjected to oral valproate therapy. The anti-epileptic therapy proved to be unsuccessful even with increasing doses. The diagnosis was corrected when we performed adequate biological investigations. This case is underlying the importance of the electrolytes profile, especially the serum phosphocalcic test, in the management of patients with new onset or recurrent epileptic seizures.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Arrab et al.)
Databáze: MEDLINE