Gut Microbiota and Colorectal Cancer: An Umbrella Review of Methodological Trends and Clinical Correlations.
| Autor: | Kasagga A; Pathology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Hawrami C; Pediatric Surgery, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Ricci E; Anesthesiology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Hailu KT; Internal medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.; Internal Medicine, Afet Speciality Clinic, Addis Ababa, ETH., Salib K; Internal Medicine, St Mary El zaytoun, Cairo, EGY., Savithri Nandeesha S; Internal Medicine, Karnataka Institute of Medical Sciences, Hubli, IND.; Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Hamid P; Neurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Feb 14; Vol. 16 (2), pp. e54210. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.54210 |
| Abstrakt: | In this umbrella review, we analyze the effect of gut microbiota on the development and progression of colorectal cancer (CRC), a global health challenge. Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines, we searched multiple databases for the most relevant systematic reviews and meta-analyses from 2000 to 2023. We identified 20 articles that met our inclusion criteria. The findings include the identification of specific microbiota markers, such as Fusobacterium nucleatum , for potential early diagnosis and improvement of disease treatment. This thorough study not only establishes the connection between microbiota and CRC but also provides valuable knowledge for future research in developing microbiome-centered treatments and preventive methods. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Kasagga et al.) |
| Databáze: | MEDLINE |
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