Does the use of tibial stem extensions reduce the risk of aseptic loosening in obese patients undergoing primary total knee arthroplasty: A systematic review and meta-analysis.

Autor: Zhou Y; Department of Orthopaedic Surgery, St. Vincent's Hospital, Melbourne, Victoria, Australia. Electronic address: Yushy.zhou@student.unimelb.edu.au., Rele S; Department of Orthopaedic Surgery, St. Vincent's Hospital, Melbourne, Victoria, Australia., Elsewaisy O; Department of Orthopaedic Surgery, St. Vincent's Hospital, Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: The Knee [Knee] 2024 Jun; Vol. 48, pp. 35-45. Date of Electronic Publication: 2024 Mar 16.
DOI: 10.1016/j.knee.2024.02.009
Abstrakt: Background: This study aimed to compare the risk of revision for aseptic loosening in obese (body mass index >30 kg/m 2 ) patients with stemmed (ST) versus non-stemmed (NST) tibial implants in primary total knee arthroplasty (TKA).
Methods: A systematic review and meta-analysis were conducted following PRISMA and MOOSE guidelines. Studies reporting a direct comparison between ST and NST tibial implants in obese patients were included. The primary outcome of interest was revision for aseptic loosening. Outcomes were analysed using meta-analysis of relative risk. Risk of bias assessment was performed using the Newcastle-Ottawa Scale for observational studies and the RoB-2 Cochrane tool for randomised studies.
Results: Seven studies met the selection criteria, consisting of four cohort studies and three randomised controlled trials. Mean follow up time for the eligible cohort was 62.6 months. Meta-analysis demonstrated a statistically significant reduction in the risk of aseptic revision in the ST group compared with the NST group (risk ratio 0.25, 95% confidence interval 0.07 to 0.92). After removal of all zero-event studies, the results remained in favour of the ST group (risk ratio 0.15, 95% confidence interval 0.03 to 0.64).
Conclusions: This study found that obese patients undergoing TKA with stemmed tibial implants may have a lower risk of aseptic revision compared with those with non-stemmed tibial implants. However, due to the lack of high-quality literature available, our study is unable to draw a definitive conclusion on this matter. We suggest that this topic should be re-evaluated using higher-quality study methods, particularly national joint registries studies and randomised controlled trials.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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