Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19.

Autor: Souza-Silva NG; Centro de Tecnologia em Medicina Molecular (CTMM), Universidade Federal de Minas Gerais (UFMG), Av Alfredo Balena 190, Belo Horizonte, MG, Brazil., Rosa DV; Centro de Tecnologia em Medicina Molecular (CTMM), Universidade Federal de Minas Gerais (UFMG), Av Alfredo Balena 190, Belo Horizonte, MG, Brazil., de Paula JJ; Centro de Tecnologia em Medicina Molecular (CTMM), Universidade Federal de Minas Gerais (UFMG), Av Alfredo Balena 190, Belo Horizonte, MG, Brazil; Departamento de Psiquiatria, Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil., Coimbra RS; Neurogenômica/Imunopatologia, Instituto René Rachou, Fiocruz, Belo Horizonte, MG, Brazil., Miranda DM; Centro de Tecnologia em Medicina Molecular (CTMM), Universidade Federal de Minas Gerais (UFMG), Av Alfredo Balena 190, Belo Horizonte, MG, Brazil; Departamento de Pediatria, Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil., Romano-Silva MA; Centro de Tecnologia em Medicina Molecular (CTMM), Universidade Federal de Minas Gerais (UFMG), Av Alfredo Balena 190, Belo Horizonte, MG, Brazil; Departamento de Psiquiatria, Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil. Electronic address: romano-silva@ufmg.br.
Jazyk: angličtina
Zdroj: Journal of neuroimmunology [J Neuroimmunol] 2024 Apr 15; Vol. 389, pp. 578327. Date of Electronic Publication: 2024 Mar 05.
DOI: 10.1016/j.jneuroim.2024.578327
Abstrakt: Individuals who experience mild COVID-19 can suffer from long-lasting cognitive symptoms. Notably, 26% of these individuals experience difficulties with visuospatial abilities six months after infection. However, among those who initially exhibited visuoconstructive impairments, 66% showed improvement or complete reversal over time. Additionally, changes in cytokine levels, particularly CCL11, HGF, and CXCL10, were observed. These results suggest a potential link between ongoing cognitive issues and elevated levels of pro-inflammatory cytokines, which merits further investigation.
Competing Interests: Declaration of competing interest None
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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