Metaplastic Breast Cancer with Squamous Differentiation: Beyond the Recognized Statistics.
| Autor: | Fallatah RZ; College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Boumarah DN; Department of Surgery, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, College of Medicine, Dammam, Saudi Arabia., Hajjaj G; Department of Surgery, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, College of Medicine, Dammam, Saudi Arabia., Alkhars AA; College of Medicine, King Fahad Hospital in Hofuf, Saudi Arabia., AlDuhileb M; Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia. |
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| Jazyk: | angličtina |
| Zdroj: | Medical archives (Sarajevo, Bosnia and Herzegovina) [Med Arch] 2024; Vol. 78 (1), pp. 75-77. |
| DOI: | 10.5455/medarh.2024.78.75-77 |
| Abstrakt: | Background: Metaplastic breast cancer is a clinically rare subtype of breast carcinomas, accounting for less than 1% of all breast neoplasms, and was not officially recognized till the end of the 20th century as an independent pathological diagnosis. Objective: In this paper, we report a case of metaplastic breast cancer with squamous differentiation in a 51-year-old female, with a succinct review of the literature. Case Report: The patient presented to our outpatient department with a complaint of left breast mass for 2 months duration with a diagnostic workup found to be grade three metaplastic carcinoma with squamous differentiation. The management decision was to proceed with neoadjuvant chemotherapy, followed by surgical intervention based on the tumor cell response to neoadjuvant therapy. Conclusion: Metaplastic breast cancer represents a rare clinical entity, encountered in a minority of patients. The clinical presentation of metaplastic carcinomas in general is similar to other breast cancers, however, metaplastic breast cancer tend to present in later stages as a rapidly growing mass with poor prognosis. The recognized poor prognosis along with rarity necessities having a high index of suspicion for early detection and appropriate management of metaplastic breast cancer. Competing Interests: None declared. (© 2024 Rania Zaki Fallatah, Dhuha N. Boumarah, Ghadeer Hajjaj, Abdullah Ahmed Alkhars, Mohammed AlDuhileb.) |
| Databáze: | MEDLINE |
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