Screening for latent tuberculosis in migrants-status quo and future challenges.

Autor:	Petersen E; PandemiX Center of Excellence, Roskilde University, Roskilde, Denmark; European Society for Clinical Microbiology and Infectious Diseases Task Force for Emerging Infections, Basel, Switzerland; International Society for Infectious Diseases, Boston, MA, USA., Al-Abri S; Directorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman. Electronic address: salabri@gmail.com., Al-Jardani A; Central Public Health Laboratory, Ministry of Health, Muscat, Oman., Memish ZA; Research and Innovation Center, King Saud Medical City, Ministry of Health & College of Medicine, Al Faisal University, Riyadh, Saudi Arabia; Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Aklillu E; Department of Global Public Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Ntoumi F; Fondation Congolaise pour la Recherche Médicale, Brazzaville, People's Republic of Congo; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany., Mwaba P; UNZA-UCLMS Research and Training Program, UTH, Lusaka, Zambia; Lusaka Apex Medical University, Faculty of Medicine, Lusaka, Zambia., Wejse C; Department of Public Health, Faculty of Health Science, Aarhus University, Aarhus, Denmark., Zumla A; Department of Infection, Centre for Clinical Microbiology, Division of Infection and Immunity, University College London, London, United Kingdom; NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, United Kingdom., Al-Yaquobi F; Directorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2024 Apr; Vol. 141S, pp. 107002. Date of Electronic Publication: 2024 Mar 11.
DOI:	10.1016/j.ijid.2024.107002
Abstrakt:	Objectives: To review the evidence that migrants from tuberculosis (TB) high-incidence countries migrating to TB low-incidence countries significantly contribute to active TB cases in the counties of destination, primarily through reactivation of latent TB. Methods: This is a narrative review. The different screening programs in the countries of destination are reviewed either based on screening and preventive treatment of latent TB pre or more commonly - post arrival. Results: Screening can be performed using interferon-gamma release assays (IGRA) or tuberculin skin tests (TST). Preventive treatment of latent TB is using either monotherapy with isoniazid, or in combination with rifampicin or rifapentine. We discuss the ethical issues of preventive treatment in asymptomatic individuals and how these are addressed in different screening programs. Conclusion: Screening migrants from TB high endemic countries to TB low endemic countries is beneficial. There is a lack of standardization and agreement on screening protocols, follow up and treatment. Competing Interests: Declarations of competing interest The authors have no competing interests to declare. (Copyright © 2024. Published by Elsevier Ltd.)
Databáze:	MEDLINE
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