Why is HSO 5 - so effective against bacteria? Insights into the mechanisms of Escherichia coli disinfection by unactivated peroxymonosulfate.

Autor: Tian N; School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, PR China; Universidad Politécnica de Madrid, E.T.S. de Ingenieros de Caminos, Canales y Puertos, Departamento de Ingeniería Civil: Hidráulica, Energía y Medio Ambiente, Unidad docente Ingeniería Sanitaria, c/ Profesor Aranguren, s/n, ES-28040, Madrid, Spain. Electronic address: tianna@hnust.edu.cn., Schmidt LC; Instituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, Valencia 46022, Spain., Lameiro MJA; CIEMAT-Plataforma Solar de Almería, Ctra. Senés km 4, Almería 04200, Spain; Solar Energy Research Centre (CIESOL), Joint Centre University of Almería-CIEMAT, Carretera de Sacramento s/n, Almería E-04120, Spain., Polo-López MI; CIEMAT-Plataforma Solar de Almería, Ctra. Senés km 4, Almería 04200, Spain; Solar Energy Research Centre (CIESOL), Joint Centre University of Almería-CIEMAT, Carretera de Sacramento s/n, Almería E-04120, Spain., Marín ML; Instituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, Valencia 46022, Spain., Boscá F; Instituto de Tecnología Química, Universitat Politècnica de València-Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n, Valencia 46022, Spain., González IDC; Universidad Politécnica de Madrid, E.T.S. de Ingenieros de Caminos, Canales y Puertos, Departamento de Ingeniería Civil: Hidráulica, Energía y Medio Ambiente, Unidad docente Ingeniería Sanitaria, c/ Profesor Aranguren, s/n, ES-28040, Madrid, Spain., Lehmann AH; Universidad Politécnica de Madrid, E.T.S. de Ingenieros de Caminos, Canales y Puertos, Departamento de Ingeniería Civil: Hidráulica, Energía y Medio Ambiente, Unidad docente Ingeniería Sanitaria, c/ Profesor Aranguren, s/n, ES-28040, Madrid, Spain., Giannakis S; Universidad Politécnica de Madrid, E.T.S. de Ingenieros de Caminos, Canales y Puertos, Departamento de Ingeniería Civil: Hidráulica, Energía y Medio Ambiente, Unidad docente Ingeniería Sanitaria, c/ Profesor Aranguren, s/n, ES-28040, Madrid, Spain. Electronic address: stefanos.giannakis@upm.es.
Jazyk: angličtina
Zdroj: Water research [Water Res] 2024 May 01; Vol. 254, pp. 121441. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.1016/j.watres.2024.121441
Abstrakt: This study examined the antimicrobial efficacy of peroxymonosulfate (PMS) against bacteria, using Escherichia coli (E. coli) as a model organism. Our investigation delineates the complex mechanisms exerted by unactivated PMS. Thus, an initial redox reaction between PMS and the target biomolecules of bacteria generates SO 4 •- as the pivotal reactive species for bacterial inactivation; to a lesser extent, •OH, 1 O 2 , or O 2 •- may also participate. Damage generated during oxidation was identified using an array of biochemical techniques. Specifically, redox processes are promoted by PMS and SO 4 •- targets and disrupt various components of bacterial cells, predominantly causing extracellular damage as well as intracellular lesions. Among these, external events are the key to cell death. Finally, by employing gene knockout mutants, we uncovered the role of specific gene responses in the intracellular damage induced by radical pathways. The findings of this study not only expand the understanding of PMS-mediated bacterial inactivation but also explain the ten-fold higher effectiveness of PMS than that reported for H 2 O 2 . Hence, we provide clear evidence that unactivated PMS solutions generate SO 4 •- in the presence of bacteria, and consequently, should be considered an effective disinfection method.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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