A New Methodology for Evaluation of Large Vestibular Aqueduct in CT and MRI Images.

Autor:	Ivanauskaite J; Department of Otolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany., Ivanauskaite J; Animal Health IT, MSD Czech Republic, Prague, Czech Republic., Matin-Mann F; Department of Otolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany., Giesemann AM; Institute for Interventional and Diagnostic Neuroradiology, Hannover Medical School, Hannover, Germany., Lenarz T; Department of Otolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany., Lesinski-Schiedat A; Department of Otolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany.
Jazyk:	angličtina
Zdroj:	Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology [Otol Neurotol] 2024 Apr 01; Vol. 45 (4), pp. 440-446.
DOI:	10.1097/MAO.0000000000004154
Abstrakt:	Hypothesis: Development of a new method for large vestibular aqueduct (LVA)/large endolymphatic sac anomaly (LESA) assessment using magnetic resonance imaging (MRI) and computed tomography (CT)/cone beam CT (CBCT) images. The secondary objective was to compare both modalities. Background: The gold standard for LVA diagnosis is the analysis of CT images using Valvassori and Clemis or Cincinnati criteria. The previous studies showed inconclusive results regarding the correlation between audiological and radiological data. Methods: Retrospective analysis of radiological images from 173 patients (315 ears), who were diagnosed with LVA/LESA based on CT/CBCT and/or MRI images of the temporal bone. The images obtained using both techniques were used to measure the following dimensions of vestibular aqueduct (VA)/endolymphatic duct (ED)/intraosseous endolymphatic sac (ES): width of the opening, length, and width at external aperture. In MRI images, the maximal contact diameters of the extraosseous or intraosseous ES and dura mater were measured as well. Results: LVA has been reported to be bilateral in 82% (142 patients) and unilateral in 18% (31 patients) of cases. Comparison of MRI and CT/CBCT measurements showed a moderate correlation (0.64) in external aperture, a moderate correlation (0.57) in the width of the VA opening, and a weak correlation (0.34) in length measurements (p < 0.05). Conclusion: We developed a new method to identify the heterogeneous pathology of LVA/LESA using reconstruction along the VA/ED/intraosseous ES axis, three measurements on two planes, and focus on the maximal contact diameter between the extraosseous or intraosseous ES and dura mater. Competing Interests: Conflicts of interest and source of funding: As a first author, I am disclosing that my sister Justina Ivanauskaite is working as a director of data science in Animal Health IT, MSD Czech Republic. The content of our research is not related to the products of MSD, and our partnership on this research is based on our familial relationship. In addition, I received a travel grant from the Cluster of Excellence “Hearing4all” EXC 1077/1, 30625 Hanover, Germany, to attend the ARO MidWinter 2023 meeting. For the remaining authors, none were declared. (Copyright © 2024, Otology & Neurotology, Inc.)
Databáze:	MEDLINE
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