The Role of Dietary Peptides Gluten and Casein in the Development of Autism Spectrum Disorder: Biochemical Perspectives.

Autor: Bjørklund G; Council for Nutritional and Environmental Medicine (CONEM), Toften 24, 8610, Mo i Rana, Norway. bjorklund@conem.org., Meguid NA; Research on Children with Special Needs Department, National Research Centre, Giza, Egypt.; CONEM Egypt Child Brain Research Group, National Research Centre, Giza, Egypt., Hemimi M; Research on Children with Special Needs Department, National Research Centre, Giza, Egypt., Sahakyan E; Neuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, 2 Koryun, 0025, Yerevan, Armenia.; Department of Pharmacy, Yerevan State Medical University after M. Heratsi, Yerevan, Armenia., Fereshetyan K; Neuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, 2 Koryun, 0025, Yerevan, Armenia.; Department of Biochemistry, Yerevan State Medical University after M. Heratsi, Yerevan, Armenia., Yenkoyan K; Neuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, 2 Koryun, 0025, Yerevan, Armenia. konstantin.yenkoyan@meduni.am.; Department of Biochemistry, Yerevan State Medical University after M. Heratsi, Yerevan, Armenia. konstantin.yenkoyan@meduni.am.
Jazyk: angličtina
Zdroj: Molecular neurobiology [Mol Neurobiol] 2024 Oct; Vol. 61 (10), pp. 8144-8155. Date of Electronic Publication: 2024 Mar 12.
DOI: 10.1007/s12035-024-04099-3
Abstrakt: This paper examines the role of dietary peptides gluten and casein in modulating brain function in individuals with autism spectrum disorder (ASD) from a biochemical perspective. Neurotransmitter systems and neural networks are crucial for brain function, and alterations at the biochemical level can contribute to the characteristic symptoms and behaviors of ASD. The paper explores how dietary peptides influence neurotransmitter systems and neural networks, highlighting their potential as interventions to improve brain function in ASD. The evidence suggests that dietary peptides can impact neurotransmitter synthesis, release, and receptor interactions, disrupting the balance of neurotransmitter systems and affecting neural network function. The findings underscore the potential of dietary interventions in modulating brain function in ASD and call for further research to elucidate the underlying mechanisms and optimize clinical practice. Considering individual dietary sensitivities and preferences, personalized dietary approaches may be necessary for optimal outcomes. Dietary interventions' timing, duration, and integration with other evidence-based treatments are crucial considerations. Safety considerations and regular monitoring are important to ensure the implementation of dietary interventions safely and effectively.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: