Environmental factors influence cross-talk between a heat shock protein and an oxidative stress protein modification in the lizard Gallotia galloti.

Autor: Gilbert E; School of Natural Sciences, The University of Hull, Hull, United Kingdom.; Energy and Environment Institute, The University of Hull, Hull, United Kingdom., Žagar A; National Institute of Biology, Ljubljana, Slovenia.; CIBIO Research Centre in Biodiversity and Genetic Resources, InBIO, Universidade do Porto Campus de Vairão, Vairão, Portugal., López-Darias M; Instituto de Productos Naturales y Agrobiología (IPNA-CSIC), La Laguna, Tenerife, Canary Islands, Spain., Megía-Palma R; CIBIO Research Centre in Biodiversity and Genetic Resources, InBIO, Universidade do Porto Campus de Vairão, Vairão, Portugal.; Universidad de Alcalá (UAH), Biomedicine and Biotechnology, Alcalá de Henares, Madrid, Spain.; BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Campus de Vairão, Vairão, Portugal., Lister KA; Biomedical Institute for Multimorbidity, Centre for Biomedicine, Hull York Medical School, The University of Hull, Hull, United Kingdom., Jones MD; Department of Fish and Wildlife Conservation, Virginia Tech, Blacksburg, VA, United States of America., Carretero MA; CIBIO Research Centre in Biodiversity and Genetic Resources, InBIO, Universidade do Porto Campus de Vairão, Vairão, Portugal.; BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Campus de Vairão, Vairão, Portugal.; Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Porto, Portugal., Serén N; CIBIO Research Centre in Biodiversity and Genetic Resources, InBIO, Universidade do Porto Campus de Vairão, Vairão, Portugal.; BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Campus de Vairão, Vairão, Portugal.; Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Porto, Portugal., Beltran-Alvarez P; Biomedical Institute for Multimorbidity, Centre for Biomedicine, Hull York Medical School, The University of Hull, Hull, United Kingdom., Valero KCW; School of Natural Sciences, The University of Hull, Hull, United Kingdom.; School of Biology and Environmental Science, University College Dublin, Belfield Campus, Dublin, Ireland.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Mar 12; Vol. 19 (3), pp. e0300111. Date of Electronic Publication: 2024 Mar 12 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0300111
Abstrakt: Better understanding how organisms respond to their abiotic environment, especially at the biochemical level, is critical in predicting population trajectories under climate change. In this study, we measured constitutive stress biomarkers and protein post-translational modifications associated with oxidative stress in Gallotia galloti, an insular lizard species inhabiting highly heterogeneous environments on Tenerife. Tenerife is a small volcanic island in a relatively isolated archipelago off the West coast of Africa. We found that expression of GRP94, a molecular chaperone protein, and levels of protein carbonylation, a marker of cellular stress, change across different environments, depending on solar radiation-related variables and topology. Here, we report in a wild animal population, cross-talk between the baseline levels of the heat shock protein-like GRP94 and oxidative damage (protein carbonylation), which are influenced by a range of available temperatures, quantified through modelled operative temperature. This suggests a dynamic trade-off between cellular homeostasis and oxidative damage in lizards adapted to this thermally and topologically heterogeneous environment.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Gilbert et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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