The emerging role of extracellular vesicles in bronchopulmonary dysplasia.

Autor: Ransom MA; Department of Pediatrics, Vanderbilt University Medical Center; Nashville, Tennessee, United States., Blatt AM; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States., Pua HH; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States.; Vanderbilt Center for Immunobiology and Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, United States., Sucre JMS; Department of Pediatrics, Vanderbilt University Medical Center; Nashville, Tennessee, United States.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, United States.
Jazyk: angličtina
Zdroj: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 May 01; Vol. 326 (5), pp. L517-L523. Date of Electronic Publication: 2024 Mar 12.
DOI: 10.1152/ajplung.00244.2023
Abstrakt: Extracellular vesicle (EV) biology in neonatal lung development and disease is a rapidly growing area of investigation. Although EV research in the neonatal population lags behind EV research in adult lung diseases, recent discoveries demonstrate promise in furthering our understanding of the pathophysiology of bronchopulmonary dysplasia and the potential use of EVs in the clinical setting, as both biomarkers and therapeutic agents. This review article explores some of the recent advances in this field and our evolving knowledge of the role of EVs in bronchopulmonary dysplasia.
Databáze: MEDLINE