Personal history of cancer as a risk factor for second primary lung cancer: Implications for lung cancer screening.

Autor: Nofal S; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Niu J; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Resong P; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Jin J; Information Services, Enterprise Development and Integration, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Merriman KW; Department of Tumor Registry, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Le X; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Katki H; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Heymach J; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Antonoff MB; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Ostrin E; Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Wu J; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Zhang J; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Toumazis I; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jazyk: angličtina
Zdroj: Cancer medicine [Cancer Med] 2024 Mar; Vol. 13 (5), pp. e7069.
DOI: 10.1002/cam4.7069
Abstrakt: Background: Personal history of cancer is an independent risk factor for lung cancer but is omitted from existing lung cancer screening eligibility criteria. In this study, we assess the lung cancer risk among cancer survivors and discuss potential implications for screening.
Methods: This was a retrospective, secondary analysis of data from the Surveillance, Epidemiology and End Results (SEER) registry and the MD Anderson Cancer Center (MDACC). We estimated the standardized incidence ratios (SIRs) for lung cancer by site of first primary cancer using data from SEER. We assessed the lung cancer risk among head and neck cancer survivors from MDACC using cumulative incidence and compared the risk ratios (RR) by individuals' screening eligibility status.
Results: Other than first primary lung cancer (SIR: 5.10, 95% CI: 5.01-5.18), cancer survivors in SEER with personal history of head and neck cancer (SIR: 3.71, 95% CI: 3.63-3.80) had the highest risk of developing second primary lung cancer, followed by bladder (SIR: 1.86, 95% CI: 1.81-1.90) and esophageal cancers (SIR: 1.78, 95% CI: 1.61-1.96). Head and neck cancer survivors had higher risk to develop lung cancer compared to the National Lung Screening Trial's subjects, (781 vs. 572 per 100,000 person-years, respectively). Head and neck cancer survivors ineligible for lung cancer screening seen at MDACC had significantly higher lung cancer risk than head and neck cancer survivors from SEER (RR: 1.9, p < 0.001).
Conclusion: Personal history of cancer, primarily head and neck cancer, is an independent risk factor for lung cancer and may be considered as an eligibility criterion in future lung cancer screening recommendations.
(© 2024 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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