Envisioning the Future: Nanomicelles Revolutionizing Ocular Drug Delivery.

Autor: Modi C; Department of Pharmaceutics, Anand Pharmacy College, Anand, Gujarat, India., Gadhvi V; Department of Pharmaceutics, Anand Pharmacy College, Anand, Gujarat, India., Prajapati BG; Shree S.K.Patel College of Pharmaceuticals Education and Research, Ganpat University, India.
Jazyk: angličtina
Zdroj: Pharmaceutical nanotechnology [Pharm Nanotechnol] 2024 Mar 08. Date of Electronic Publication: 2024 Mar 08.
DOI: 10.2174/0122117385286925240221111601
Abstrakt: Due to the complexities of the eye's anatomy and physiology, achieving targeted drug delivery with minimal harm to healthy eye tissues has proven to be difficult. The focus of the review is on the potential of lipid and polymer micelle-based drug delivery systems, specifically nanomicelles, to overcome these challenges and improve the absorption of insoluble drugs. Nanomicelles offer several advantages, such as enhanced drug release kinetics, increased drug incorporation, and improved formulation of hydrophobic medicines. The review provides insights into various excipients, preparation methods, and evaluation techniques used in nanomicellar-based drug delivery systems. Furthermore, the review highlights current research and patents related to nanomicelles in ocular drug delivery, suggesting growing interest and potential for future developments in this field. Nanomicelles present a promising approach that may revolutionize ocular drug delivery and open new possibilities for treating various ocular diseases while minimizing adverse effects on healthy eye tissues.
(Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Databáze: MEDLINE