Dietary Magnesium Intake Is Inversely Associated With Ulcerative Colitis: A Case-Control Study.

Autor:	Sadeghi O; Nutrition and Food Security Research Center, Department of Community Nutrition, Student Research Committee, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran., Khademi Z; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran., Saneei P; Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran., Hassanzadeh-Keshteli A; Department of Medicine, University of Alberta, Edmonton, Canada.; Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Daghaghzadeh H; Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Tavakkoli H; Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Adibi P; Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Esmaillzadeh A; Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.; Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.; Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Crohn's & colitis 360 [Crohns Colitis 360] 2024 Feb 21; Vol. 6 (1), pp. otae009. Date of Electronic Publication: 2024 Feb 21 (Print Publication: 2024).
DOI:	10.1093/crocol/otae009
Abstrakt:	Background: Ulcerative colitis (UC) causes long-lasting inflammation and ulcers in the gut. Limited observational data are available linking dietary magnesium intake and UC. In the present study, we aimed to investigate the association between dietary magnesium intake and UC in adults. Methods: The current population-based case-control study was performed on 109 UC patients and 218 age (±2 years) and sex-matched controls. The diagnosis of UC was made according to the standard criteria by a gastroenterology specialist. Dietary intakes were assessed using a validated self-administrated 106-item dish-based Food Frequency Questionnaire (FFQ). We also used a pretested questionnaire to collect data on potential confounders. Results: Individuals in the top tertile of magnesium intake were less likely to have UC compared with those in the bottom tertile. A significant inverse relationship was found between dietary magnesium intake and UC (odds ratio [OR]: 0.32, 95% confidence interval [CI]: 0.18-0.59) in the crude model. This relationship was also observed when we took several potential confounding into account (OR: 0.30, 95% CI: 0.14-0.68). Conclusions: Adherence to a magnesium-rich diet may have a role in preventing UC. However, further studies are needed to confirm our findings. Competing Interests: None declared. (© The Author(s) 2024. Published by Oxford University Press on behalf of Crohn's & Colitis Foundation.)
Databáze:	MEDLINE
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